Characterization of diterpenoids from Caesalpinia decapetala and their anti-TMV activities

Jing Xu, Xiangrong Cao, Feng Liu, Jun Ma, Xingyu Liu, Ling Tong, Guochen Su, Yasushi Ohizumi, Dongho Lee, Lizhong Wang, Yuanqiang Guo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Caesalpinia decapetala is a versatile medicinal plant belonging to the Fabaceae plant family. In our survey on plant secondary metabolites to obtain bioactive substances for the development of new agricultural anti-TMV agents, the chemical constituents of C. decapetala were investigated. This investigation led to the isolation of three new and ten known diterpenoids. Their structures including absolute configurations were elucidated based on the extensive NMR spectroscopic data analyses and the time-dependent density functional theory calculations. The following biological screenings revealed that most of these diterpenoids possessed anti-TMV activities.

Original languageEnglish
Pages (from-to)144-150
Number of pages7
JournalFitoterapia
Volume113
DOIs
Publication statusPublished - 2016 Sep 1

Keywords

  • Anti-TMV activities
  • Caesalpinia decapetala
  • Cassane-type
  • Diterpenoids
  • ECD calculations

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology
  • Drug Discovery

Fingerprint Dive into the research topics of 'Characterization of diterpenoids from Caesalpinia decapetala and their anti-TMV activities'. Together they form a unique fingerprint.

  • Cite this

    Xu, J., Cao, X., Liu, F., Ma, J., Liu, X., Tong, L., Su, G., Ohizumi, Y., Lee, D., Wang, L., & Guo, Y. (2016). Characterization of diterpenoids from Caesalpinia decapetala and their anti-TMV activities. Fitoterapia, 113, 144-150. https://doi.org/10.1016/j.fitote.2016.07.017