Characterization of U-shape streamline fibers: Methods and applications

Tuo Zhang, Hanbo Chen, Lei Guo, Kaiming Li, Longchuan Li, Shu Zhang, Dinggang Shen, Xiaoping Hu, Tianming Liu

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Diffusion tensor imaging (DTI), high angular resolution diffusion imaging (HARDI), and diffusion spectrum imaging (DSI) have been widely used in the neuroimaging field to examine the macro-scale fiber connection patterns in the cerebral cortex. However, the topographic and geometric relationships between diffusion imaging derived streamline fiber connection patterns and cortical folding patterns remain largely unknown. This paper specifically identifies and characterizes the U-shapes of diffusion imaging derived streamline fibers via a novel fiber clustering framework and examines their co-localization patterns with cortical sulci based on DTI, HARDI, and DSI datasets of human, chimpanzee and macaque brains. We verified the presence of these U-shaped streamline fibers that connect neighboring gyri by coursing around cortical sulci such as the central sulcus, pre-central sulcus, post-central sulcus, superior temporal sulcus, inferior frontal sulcus, and intra-parietal sulcus. This study also verified the existence of U-shape fibers across data modalities (DTI/HARDI/DSI) and primate species (macaque, chimpanzee and human), and suggests that the common pattern of U-shape fibers coursing around sulci is evolutionarily-preserved in cortical architectures.

Original languageEnglish
Pages (from-to)795-807
Number of pages13
JournalMedical Image Analysis
Volume18
Issue number5
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

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Keywords

  • DSI
  • DTI
  • Fiber shapes
  • HARDI
  • Shape analysis

ASJC Scopus subject areas

  • Computer Graphics and Computer-Aided Design
  • Computer Vision and Pattern Recognition
  • Radiology Nuclear Medicine and imaging
  • Health Informatics
  • Radiological and Ultrasound Technology

Cite this

Zhang, T., Chen, H., Guo, L., Li, K., Li, L., Zhang, S., Shen, D., Hu, X., & Liu, T. (2014). Characterization of U-shape streamline fibers: Methods and applications. Medical Image Analysis, 18(5), 795-807. https://doi.org/10.1016/j.media.2014.04.005