@inproceedings{b8182288becb446abdf846c93391b972,
title = "Characterizing Intra-soma Diffusion with Spherical Mean Spectrum Imaging",
abstract = "Most brain microstructure models are dedicated to the quantification of white matter microstructure, using for example sticks, cylinders, and zeppelins to model intra- and extra-axonal environments. Gray matter presents unique micro-architecture with cell bodies (somas) exhibiting diffusion characteristics that differ from axons in white matter. In this paper, we introduce a method to quantify soma microstructure, giving measures such as volume fraction, diffusivity, and kurtosis. Our method captures a spectrum of diffusion patterns and scales and does not rely on restrictive model assumptions. We show that our method yields unique and meaningful contrasts that are in agreement with histological data. We demonstrate its application in the mapping of the distinct spatial patterns of soma density in the cortex.",
author = "Huynh, {Khoi Minh} and Ye Wu and Thung, {Kim Han} and Sahar Ahmad and {Taylor IV}, {Hoyt Patrick} and Dinggang Shen and Yap, {Pew Thian}",
note = "Funding Information: This work was supported in part by NIH grants (NS093842 and EB022880). Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.; 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020 ; Conference date: 04-10-2020 Through 08-10-2020",
year = "2020",
doi = "10.1007/978-3-030-59728-3_35",
language = "English",
isbn = "9783030597276",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Science and Business Media Deutschland GmbH",
pages = "354--363",
editor = "Martel, {Anne L.} and Purang Abolmaesumi and Danail Stoyanov and Diana Mateus and Zuluaga, {Maria A.} and Zhou, {S. Kevin} and Daniel Racoceanu and Leo Joskowicz",
booktitle = "Medical Image Computing and Computer Assisted Intervention – MICCAI 2020 - 23rd International Conference, Proceedings",
address = "Germany",
}