Chemical composition and anti-stress effects of yeast hydrolysate

Hyun S. Lee, Eun Young Jung, Hyung Joo Suh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In the present study, the anti-stress effects of yeast hydrolysate (YH) were investigated. The YH consisted of crude carbohydrate (23.6%) and crude protein (68.3%) with low contents of crude ash (3.1%) and crude fat (0.3%). Also, acidic amino acids (glutamic acid+aspartic acid) were present in large quantities (14.2 and 5.0mol%, respectively). Pronase digestion had little effect on the affinity of the YH on 5-hydroxytryptamine (serotonin) and norepinephrine transporters, whereas NaIO4 oxidation of the hydrolysate decreased the affinity by about 10% at 1,000μg/mL, indicating that the periodate-labile carbohydrate moiety played a leading role in the affinity effects of the carbohydrate in YH. As a result of brain mapping after the administration of the YH for 3 days in human subjects, a symmetrical distribution of theta and alpha waves in the central and parietal lobes was observed. This brain mapping pattern of theta and alpha wave distribution appears in a psychologically stable state. The YH groups showed improvements in Beck Depression Inventory and Beck Anxiety Inventory scores after YH administration for 2 weeks. Treatment also seemed to have a more significant (P<.05) impact on the somatic manifestations of anxiety as indexed by the Beck Anxiety Inventory scores. Food materials used as a source of YH have been found to be associated with increases in alertness and adaptation to stress.

Original languageEnglish
Pages (from-to)1281-1285
Number of pages5
JournalJournal of Medicinal Food
Volume12
Issue number6
DOIs
Publication statusPublished - 2009 Dec 1

Fingerprint

Yeasts
Brain Mapping
Anxiety
Carbohydrates
Equipment and Supplies
Norepinephrine Plasma Membrane Transport Proteins
Acidic Amino Acids
Serotonin Plasma Membrane Transport Proteins
Pronase
Parietal Lobe
Aspartic Acid
Glutamic Acid
Digestion
Serotonin
Fats
Depression
Food
Proteins

Keywords

  • Beck anxiety inventory
  • Beck depression inventory
  • Brain mapping
  • Stress

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Chemical composition and anti-stress effects of yeast hydrolysate. / Lee, Hyun S.; Jung, Eun Young; Suh, Hyung Joo.

In: Journal of Medicinal Food, Vol. 12, No. 6, 01.12.2009, p. 1281-1285.

Research output: Contribution to journalArticle

Lee, Hyun S. ; Jung, Eun Young ; Suh, Hyung Joo. / Chemical composition and anti-stress effects of yeast hydrolysate. In: Journal of Medicinal Food. 2009 ; Vol. 12, No. 6. pp. 1281-1285.
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