Chondromyxoid fibroma of the distal phalanx of the great toe

A tumor with unusual histological findings

Young Sik Kim, Seung Ju Jeon, Sang Hoon Cha, Insun Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Chondromyxoid fibroma (CMF) rarely arises in the distal phalanx of the foot and less than 20 cases have been reported in the literature. It has also been known to show a wide spectrum of histology mimicking other primary bone tumors. An unusual case of CMF arising in the distal phalanx of the left great toe is reported because of its unique anatomic site of origin and histology. A 53-year-old female presented with a slow growing, painful great toe of the left foot which she had for 3 years. She had first noticed the mass 25 years ago. On admission, plain X-ray revealed an osteolytic mass with a sclerotic margin expanding to the distal phalanx of the great toe. Interestingly, the lesion was microscopically composed of hypercellular chondromyxoid lobules separated by hypocellular fibrous tissue, which is in contrast to the typical histology of CMF. In addition, the lesion showed an aggregate of tumor cells with pleomorphic multinucleate or giant nuclei within the chondromyxoid matrix, which were not similar to the osteoclast- like type. Perhaps these unusual histological findings may be associated with its long duration and presenting location.

Original languageEnglish
Pages (from-to)739-743
Number of pages5
JournalPathology International
Volume48
Issue number9
Publication statusPublished - 1998 Oct 9

Fingerprint

Toe Phalanges
Hallux
Fibroma
Histology
Foot
Neoplasms
Osteoclasts
X-Rays
Bone and Bones

Keywords

  • Chondromyxoid fibroma
  • Distal phalanx
  • Foot
  • Histology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Chondromyxoid fibroma of the distal phalanx of the great toe : A tumor with unusual histological findings. / Kim, Young Sik; Jeon, Seung Ju; Cha, Sang Hoon; Kim, Insun.

In: Pathology International, Vol. 48, No. 9, 09.10.1998, p. 739-743.

Research output: Contribution to journalArticle

@article{e1a40208168a416087bdeefe25e5b712,
title = "Chondromyxoid fibroma of the distal phalanx of the great toe: A tumor with unusual histological findings",
abstract = "Chondromyxoid fibroma (CMF) rarely arises in the distal phalanx of the foot and less than 20 cases have been reported in the literature. It has also been known to show a wide spectrum of histology mimicking other primary bone tumors. An unusual case of CMF arising in the distal phalanx of the left great toe is reported because of its unique anatomic site of origin and histology. A 53-year-old female presented with a slow growing, painful great toe of the left foot which she had for 3 years. She had first noticed the mass 25 years ago. On admission, plain X-ray revealed an osteolytic mass with a sclerotic margin expanding to the distal phalanx of the great toe. Interestingly, the lesion was microscopically composed of hypercellular chondromyxoid lobules separated by hypocellular fibrous tissue, which is in contrast to the typical histology of CMF. In addition, the lesion showed an aggregate of tumor cells with pleomorphic multinucleate or giant nuclei within the chondromyxoid matrix, which were not similar to the osteoclast- like type. Perhaps these unusual histological findings may be associated with its long duration and presenting location.",
keywords = "Chondromyxoid fibroma, Distal phalanx, Foot, Histology",
author = "Kim, {Young Sik} and Jeon, {Seung Ju} and Cha, {Sang Hoon} and Insun Kim",
year = "1998",
month = "10",
day = "9",
language = "English",
volume = "48",
pages = "739--743",
journal = "Pathology International",
issn = "1320-5463",
publisher = "Wiley-Blackwell",
number = "9",

}

TY - JOUR

T1 - Chondromyxoid fibroma of the distal phalanx of the great toe

T2 - A tumor with unusual histological findings

AU - Kim, Young Sik

AU - Jeon, Seung Ju

AU - Cha, Sang Hoon

AU - Kim, Insun

PY - 1998/10/9

Y1 - 1998/10/9

N2 - Chondromyxoid fibroma (CMF) rarely arises in the distal phalanx of the foot and less than 20 cases have been reported in the literature. It has also been known to show a wide spectrum of histology mimicking other primary bone tumors. An unusual case of CMF arising in the distal phalanx of the left great toe is reported because of its unique anatomic site of origin and histology. A 53-year-old female presented with a slow growing, painful great toe of the left foot which she had for 3 years. She had first noticed the mass 25 years ago. On admission, plain X-ray revealed an osteolytic mass with a sclerotic margin expanding to the distal phalanx of the great toe. Interestingly, the lesion was microscopically composed of hypercellular chondromyxoid lobules separated by hypocellular fibrous tissue, which is in contrast to the typical histology of CMF. In addition, the lesion showed an aggregate of tumor cells with pleomorphic multinucleate or giant nuclei within the chondromyxoid matrix, which were not similar to the osteoclast- like type. Perhaps these unusual histological findings may be associated with its long duration and presenting location.

AB - Chondromyxoid fibroma (CMF) rarely arises in the distal phalanx of the foot and less than 20 cases have been reported in the literature. It has also been known to show a wide spectrum of histology mimicking other primary bone tumors. An unusual case of CMF arising in the distal phalanx of the left great toe is reported because of its unique anatomic site of origin and histology. A 53-year-old female presented with a slow growing, painful great toe of the left foot which she had for 3 years. She had first noticed the mass 25 years ago. On admission, plain X-ray revealed an osteolytic mass with a sclerotic margin expanding to the distal phalanx of the great toe. Interestingly, the lesion was microscopically composed of hypercellular chondromyxoid lobules separated by hypocellular fibrous tissue, which is in contrast to the typical histology of CMF. In addition, the lesion showed an aggregate of tumor cells with pleomorphic multinucleate or giant nuclei within the chondromyxoid matrix, which were not similar to the osteoclast- like type. Perhaps these unusual histological findings may be associated with its long duration and presenting location.

KW - Chondromyxoid fibroma

KW - Distal phalanx

KW - Foot

KW - Histology

UR - http://www.scopus.com/inward/record.url?scp=15444349269&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=15444349269&partnerID=8YFLogxK

M3 - Article

VL - 48

SP - 739

EP - 743

JO - Pathology International

JF - Pathology International

SN - 1320-5463

IS - 9

ER -