Chorea due to diabetic hyperglycemia and uremia: Distinct clinical and imaging features

Young Jin Kim, Sang Joon Kim, Juyeon Kim, Mi Jung Kim, Ki Ju Kim, Hyukjun Yoon, Sung Reul Kim, Sun Ju Chung

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study was undertaken to describe the clinical and imaging characteristics of patients with chorea associated with nonketotic hyperglycemia (C-NKH) in comparison with patients with chorea associated with uremia (C-URE). We retrospectively analyzed the clinical data of consecutive 10 C-NKH and five C-URE patients who were treated between January 1, 2001 and January 31, 2013. Women were more frequently affected by C-NKH (70% vs. 30%) and C-URE (80% vs. 20%) compared with men. The C-NKH patients demonstrated T1-hyperintense and inhomogeneous lesions in the basal ganglia, whereas C-URE patients demonstrated T2-hyperintense and homogeneous lesions in the basal ganglia. The mean time for chorea resolution after treatment was significantly shorter in C-NKH patients than in C-URE patients (4.4±2.6 d vs. 73.8±14.2 d, respectively; P=0.005). The clinical and imaging features are remarkably different between C-NKH and C-URE patients, suggesting distinct pathogenic mechanisms.

Original languageEnglish
Pages (from-to)419-422
Number of pages4
JournalMovement Disorders
Volume30
Issue number3
DOIs
Publication statusPublished - 2015 Mar 1
Externally publishedYes

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Chorea
Uremia
Hyperglycemia
Basal Ganglia

Keywords

  • Chorea
  • Diabetes
  • Hyperglycemia
  • Magnetic resonance imaging
  • Uremia

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Kim, Y. J., Kim, S. J., Kim, J., Kim, M. J., Kim, K. J., Yoon, H., ... Chung, S. J. (2015). Chorea due to diabetic hyperglycemia and uremia: Distinct clinical and imaging features. Movement Disorders, 30(3), 419-422. https://doi.org/10.1002/mds.26148

Chorea due to diabetic hyperglycemia and uremia : Distinct clinical and imaging features. / Kim, Young Jin; Kim, Sang Joon; Kim, Juyeon; Kim, Mi Jung; Kim, Ki Ju; Yoon, Hyukjun; Kim, Sung Reul; Chung, Sun Ju.

In: Movement Disorders, Vol. 30, No. 3, 01.03.2015, p. 419-422.

Research output: Contribution to journalArticle

Kim, YJ, Kim, SJ, Kim, J, Kim, MJ, Kim, KJ, Yoon, H, Kim, SR & Chung, SJ 2015, 'Chorea due to diabetic hyperglycemia and uremia: Distinct clinical and imaging features', Movement Disorders, vol. 30, no. 3, pp. 419-422. https://doi.org/10.1002/mds.26148
Kim, Young Jin ; Kim, Sang Joon ; Kim, Juyeon ; Kim, Mi Jung ; Kim, Ki Ju ; Yoon, Hyukjun ; Kim, Sung Reul ; Chung, Sun Ju. / Chorea due to diabetic hyperglycemia and uremia : Distinct clinical and imaging features. In: Movement Disorders. 2015 ; Vol. 30, No. 3. pp. 419-422.
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