Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange

Jeong Won Lee, Hyo Sung Jung, Pil Seung Kwon, Jong Wan Kim, Richard A. Bartsch, Youngmee Kim, Sung Jin Kim, Jong Seung Kim

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

(Chemical Equation Presented) (Figure Presented) The fluorescence of NABQ increases remarkably in the presence of Zn2+ and is quenched by Hg2+. As shown by confocal imaging, NABQ-Zn2+ can penetrate cells, where the bound Zn2+ is exchanged for Hg 2+. This results in the concomitant export of Hg2+ from the cells, showing that NABQ can act as a Zn2+ carrier and as a Hg2+ extracting agent in living cells.

Original languageEnglish
Pages (from-to)3801-3804
Number of pages4
JournalOrganic Letters
Volume10
Issue number17
DOIs
Publication statusPublished - 2008 Dec 1

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cells
fluorescence
Fluorescence
Cells
Imaging techniques
N-acetyl-4-benzoquinoneimine

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Lee, J. W., Jung, H. S., Kwon, P. S., Kim, J. W., Bartsch, R. A., Kim, Y., ... Kim, J. S. (2008). Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange. Organic Letters, 10(17), 3801-3804. https://doi.org/10.1021/ol801482n

Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange. / Lee, Jeong Won; Jung, Hyo Sung; Kwon, Pil Seung; Kim, Jong Wan; Bartsch, Richard A.; Kim, Youngmee; Kim, Sung Jin; Kim, Jong Seung.

In: Organic Letters, Vol. 10, No. 17, 01.12.2008, p. 3801-3804.

Research output: Contribution to journalArticle

Lee, JW, Jung, HS, Kwon, PS, Kim, JW, Bartsch, RA, Kim, Y, Kim, SJ & Kim, JS 2008, 'Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange', Organic Letters, vol. 10, no. 17, pp. 3801-3804. https://doi.org/10.1021/ol801482n
Lee JW, Jung HS, Kwon PS, Kim JW, Bartsch RA, Kim Y et al. Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange. Organic Letters. 2008 Dec 1;10(17):3801-3804. https://doi.org/10.1021/ol801482n
Lee, Jeong Won ; Jung, Hyo Sung ; Kwon, Pil Seung ; Kim, Jong Wan ; Bartsch, Richard A. ; Kim, Youngmee ; Kim, Sung Jin ; Kim, Jong Seung. / Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange. In: Organic Letters. 2008 ; Vol. 10, No. 17. pp. 3801-3804.
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