Chronic cavitary pulmonary histoplasmosis in a non-HIV and immunocompromised patient without overseas travel history

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Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old female was admitted to the hospital for evaluation of multiple lung nodules. A computed tomography (CT) scan of the chest showed multiple ill-defined consolidations and cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely following itraconazole treatment. This is the first case report of pulmonary histoplasmosis unconnected with either HIV infection or endemicity in Korea.

Original languageEnglish
Pages (from-to)871-874
Number of pages4
JournalYonsei Medical Journal
Issue number3
Publication statusPublished - 2015 Jan 1



  • Histoplasma capsulatum
  • Immunocompromised host
  • Korea

ASJC Scopus subject areas

  • Medicine(all)

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