Chronic cavitary pulmonary histoplasmosis in a non-HIV and immunocompromised patient without overseas travel history

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4 Citations (Scopus)

Abstract

Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old female was admitted to the hospital for evaluation of multiple lung nodules. A computed tomography (CT) scan of the chest showed multiple ill-defined consolidations and cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely following itraconazole treatment. This is the first case report of pulmonary histoplasmosis unconnected with either HIV infection or endemicity in Korea.

Original languageEnglish
Pages (from-to)871-874
Number of pages4
JournalYonsei Medical Journal
Volume56
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

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Histoplasmosis
Immunocompromised Host
Lung
Korea
Tomography
Histoplasma
Biopsy
Itraconazole
HIV Infections
Thorax

Keywords

  • Histoplasma capsulatum
  • Immunocompromised host
  • Korea

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old female was admitted to the hospital for evaluation of multiple lung nodules. A computed tomography (CT) scan of the chest showed multiple ill-defined consolidations and cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely following itraconazole treatment. This is the first case report of pulmonary histoplasmosis unconnected with either HIV infection or endemicity in Korea.",
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