Chronic obstructive pulmonary disease assessment test can predict depression: A prospective multi-center study

Young Seok Lee, Sunghoon Park, Yeon Mok Oh, Sang Do Lee, Sung Woo Park, Young Sam Kim, Kwang Ho In, Bock Hyun Jung, Kwan Ho Lee, Seung Won Ra, Yong Il Hwang, Yong Bum Park, Ki Suck Jung

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)

    Abstract

    This study was conducted to investigate the association between the chronic obstructive pulmonary disease (COPD) assessment test (CAT) and depression in COPD patients. The Korean versions of the CAT and patient health questionnaire-9 (PHQ-9) were used to assess COPD symptoms and depressive disorder, respectively. In total, 803 patients with COPD were enrolled from 32 hospitals and the prevalence of depression was 23.8%. The CAT score correlated well with the PHQ-9 score (r = 0.631; P < 0.001) and was significantly associated with the presence of depression (ß ± standard error, 0.452 ± 0.020; P < 0.001). There was a tendency toward increasing severity of depression in patients with higher CAT scores. By assessment groups based on the 2011 Global Initiative for Chronic Obstructive Lung Disease guidelines, the prevalence of depression was affected more by current symptoms than by airway limitation. The area under the receiver operating characteristic curve for the CAT was 0.849 for predicting depression, and CAT scores = 21 had the highest accuracy rate (80.6%). Among the eight CAT items, energy score showed the best correlation and highest power of discrimination. CAT scores are significantly associated with the presence of depression and have good performance for predicting depression in COPD patients

    Original languageEnglish
    Pages (from-to)1048-1054
    Number of pages7
    JournalJournal of Korean medical science
    Volume28
    Issue number7
    DOIs
    Publication statusPublished - 2013 Jul

    Keywords

    • COPD Assessment Test
    • Chronic Obstructive
    • Depression
    • Pulmonary Disease

    ASJC Scopus subject areas

    • Medicine(all)

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