Chrysophanol Induces Apoptosis of Choriocarcinoma Through Regulation of ROS and the AKT and ERK1/2 Pathways

Medicine & Life Sciences

• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 10%
• 70-kDa Ribosomal Protein S6 Kinases 6%
• Anthraquinones 6%
• Apoptosis 36%
• Cell Survival 3%
• Choriocarcinoma 74%
• chrysophanic acid 100%
• MAP Kinase Signaling System 65%
• Mitochondrial Membrane Potential 4%
• Neoplasms 2%
• Oxidative Stress 3%
• Pharmacology 3%
• Phosphatidylinositol 3-Kinases 4%
• Phosphorylation 3%
• Proteins 1%
• Rheum 6%
• Signal Transduction 3%
• Therapeutic Uses 3%
• Therapeutics 3%
• TP protocol 6%
• U 0126 17%
• Western Blotting 3%

Chemical Compounds

• Anthraquinone 5%
• Cell Viability 5%
• Chrysophanol 92%
• Cisplatin 5%
• Depolarization 6%
• LY294002 19%
• Membrane Potential 5%
• Oxidative Stress 5%
• Paclitaxel 6%
• Protein 2%
• Signal Transduction 5%
• U0126 31%