Circumferential bone grafting around an absorbable gelatin sponge core reduced the amount of grafted bone in the induced membrane technique for critical-size defects of long bones

Jae Woo Cho, Jinil Kim, Won Tae Cho, Jin Kak Kim, Jong Hoon Song, Hyung Jin Kim, Alain C. Masquelet, Jong-Keon Oh

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objectives The objectives of the study were to introduce a circumferential bone graft around an absorbable gelatin sponge core using an induced membrane technique, to assess its ability to reduce the required amount of graft and to maintain the bone graft, and to evaluate the clinical outcomes in the management of critical-size bone defects. Patients and methods Circumferential bone grafting using a staged induced membrane technique for managing critical-size bone defects was performed in 21 patients. Postoperative computed tomography scans were performed 7 days after Hemovac drain removal and 3 months after bone grafting. Volumetric measurements of the defect size, gelatin sponge proportion, and amount of grafted bone were performed by two independent observers using three-dimensional (3D) software. Results The critical-size defects were located at the metadiaphyseal area of 11 tibias, eight femurs, and two humeri. The average defect size was 8.9 cm in length and 65.2 cm3 in volume. The absorbable gelatin sponge core replaced 21.4% (average) of the defect volume. There was no significant deterioration in the shape of the grafted bone among the serial 3D models. Eighteen patients (86%) were healed radiographically at 9.1 months (average). Conclusion Our study suggests that circumferential bone grafting in association with the induced membrane technique could reduce the required amount of bone graft and adequately maintain graft position and shape, with favourable clinical outcomes.

Original languageEnglish
Pages (from-to)2292-2305
Number of pages14
JournalInjury
Volume48
Issue number10
DOIs
Publication statusPublished - 2017 Oct 1

Fingerprint

Absorbable Gelatin Sponge
Bone Transplantation
Bone and Bones
Membranes
Transplants
Humerus
Porifera
Gelatin
Tibia
Femur
Software
Tomography

Keywords

  • Absorbable gelatin sponge
  • Autogenous bone graft
  • Critical-size bone defect
  • Induced membrane technique
  • Infected non-union
  • Posttraumatic osteomyelitis

ASJC Scopus subject areas

  • Emergency Medicine
  • Orthopedics and Sports Medicine

Cite this

Circumferential bone grafting around an absorbable gelatin sponge core reduced the amount of grafted bone in the induced membrane technique for critical-size defects of long bones. / Cho, Jae Woo; Kim, Jinil; Cho, Won Tae; Kim, Jin Kak; Song, Jong Hoon; Kim, Hyung Jin; Masquelet, Alain C.; Oh, Jong-Keon.

In: Injury, Vol. 48, No. 10, 01.10.2017, p. 2292-2305.

Research output: Contribution to journalArticle

Cho, Jae Woo ; Kim, Jinil ; Cho, Won Tae ; Kim, Jin Kak ; Song, Jong Hoon ; Kim, Hyung Jin ; Masquelet, Alain C. ; Oh, Jong-Keon. / Circumferential bone grafting around an absorbable gelatin sponge core reduced the amount of grafted bone in the induced membrane technique for critical-size defects of long bones. In: Injury. 2017 ; Vol. 48, No. 10. pp. 2292-2305.
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abstract = "Objectives The objectives of the study were to introduce a circumferential bone graft around an absorbable gelatin sponge core using an induced membrane technique, to assess its ability to reduce the required amount of graft and to maintain the bone graft, and to evaluate the clinical outcomes in the management of critical-size bone defects. Patients and methods Circumferential bone grafting using a staged induced membrane technique for managing critical-size bone defects was performed in 21 patients. Postoperative computed tomography scans were performed 7 days after Hemovac drain removal and 3 months after bone grafting. Volumetric measurements of the defect size, gelatin sponge proportion, and amount of grafted bone were performed by two independent observers using three-dimensional (3D) software. Results The critical-size defects were located at the metadiaphyseal area of 11 tibias, eight femurs, and two humeri. The average defect size was 8.9 cm in length and 65.2 cm3 in volume. The absorbable gelatin sponge core replaced 21.4{\%} (average) of the defect volume. There was no significant deterioration in the shape of the grafted bone among the serial 3D models. Eighteen patients (86{\%}) were healed radiographically at 9.1 months (average). Conclusion Our study suggests that circumferential bone grafting in association with the induced membrane technique could reduce the required amount of bone graft and adequately maintain graft position and shape, with favourable clinical outcomes.",
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