Cisatracurium pretreatment with tourniquet reduces propofol injection pain: A double-blind randomized controlled trial

Yun-Hee Kim, Jin Namgung, Choon Hak Lim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: To investigate the efficacy of pretreatment with cisatracurium for prevention of pain associated with propofol injection, and compare its efficacy with that of lidocaine. Methods: Patients undergoing general anaesthesia were randomized to receive normal saline (control group), lidocaine (0.5 mg/kg), 0.03 mg/kg cisatracurium or 0.15 mg/kg cisatracurium. All drugs were administered into the largest dorsal vein of the hand with venous occlusion for 30 s, followed by propofol (0.5 mg/kg). Pain was evaluated using a four-point scale. Results: The incidence and severity of pain was significantly lower in the lidocaine and 0.15 mg/kg cisatracurium groups than the control and 0.03 mg/kg cisatracurium groups (n=50/group). There was no significant difference between the lidocaine and 0.15 mg/kg cisatracurium groups in the incidence and severity of pain. Conclusions: 0.15 mg/kg cisatracurium effectively decreases the incidence and severity of pain induced by propofol injection without any significant complications.

Original languageEnglish
Pages (from-to)360-367
Number of pages8
JournalJournal of International Medical Research
Volume42
Issue number2
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Tourniquets
Propofol
Randomized Controlled Trials
Pain
Injections
Lidocaine
Incidence
Control Groups
cisatracurium
General Anesthesia
Veins
Hand
Pharmaceutical Preparations

Keywords

  • Cisatracurium
  • general anaesthesia
  • propofol injection pain

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

Cite this

Cisatracurium pretreatment with tourniquet reduces propofol injection pain : A double-blind randomized controlled trial. / Kim, Yun-Hee; Namgung, Jin; Lim, Choon Hak.

In: Journal of International Medical Research, Vol. 42, No. 2, 01.01.2014, p. 360-367.

Research output: Contribution to journalArticle

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