Abstract
In this work, we report a novel stimuli-sensitive probe working on the principle of the cleavage-induced fluorescent change via hydrophilicity control. In our Si-Py-Ac-PEG probe, cleavage of hydrophilic PEG moiety in acidic environment induces hydrophobic interaction of pyrenes to increase their excimer emission. Our fluorescent probe (Si-Py-Ac-PEG) was successfully applied to the spotting microarray and nanoparticle suspension to demonstrate the potential of biological applications, i.e. protein chip and bioimaging.
Original language | English |
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Pages (from-to) | 149-154 |
Number of pages | 6 |
Journal | Journal of Photochemistry and Photobiology A: Chemistry |
Volume | 188 |
Issue number | 2-3 |
DOIs | |
Publication status | Published - 2007 May 20 |
Keywords
- Biomedical imaging
- Cleavage
- Excimer emission
- Hydrophilicity control
- Microarray
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)
- Physics and Astronomy(all)