Abstract
In this work, we report a novel stimuli-sensitive probe working on the principle of the cleavage-induced fluorescent change via hydrophilicity control. In our Si-Py-Ac-PEG probe, cleavage of hydrophilic PEG moiety in acidic environment induces hydrophobic interaction of pyrenes to increase their excimer emission. Our fluorescent probe (Si-Py-Ac-PEG) was successfully applied to the spotting microarray and nanoparticle suspension to demonstrate the potential of biological applications, i.e. protein chip and bioimaging.
| Original language | English |
|---|---|
| Pages (from-to) | 149-154 |
| Number of pages | 6 |
| Journal | Journal of Photochemistry and Photobiology A: Chemistry |
| Volume | 188 |
| Issue number | 2-3 |
| DOIs | |
| Publication status | Published - 2007 May 20 |
Keywords
- Biomedical imaging
- Cleavage
- Excimer emission
- Hydrophilicity control
- Microarray
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)
- Physics and Astronomy(all)
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Lim, C. K., Lee, J. S., Ha, T. H., Kwon, I. C., Ahn, C. H., & Park, S. Y. (2007). Cleavage-induced fluorescence change via hydrophilicity control: A new strategy for biological application. Journal of Photochemistry and Photobiology A: Chemistry, 188(2-3), 149-154. https://doi.org/10.1016/j.jphotochem.2006.12.002