Clinical Analysis of Pediatric Thyroid Cancer: A Single Medical Institution Experience of 18 Years

Hyung Kwon Byeon, Sang Bin Kim, Hyeon Seok Oh, Hong Kyu Kim, In Hak Choi, Hyunjung Kim, Jae Gu Cho, Kyung Ho Oh, Seung Kuk Baek, Jeong Soo Woo, Soon Young Kwon, Hoon Yub Kim, Kwang Yoon Jung

Research output: Contribution to journalArticle

Abstract

Objective: The incidence of pediatric thyroid cancer is relatively low compared to the disease in adults. This study aims to present the data in our institution on pediatric thyroid cancer patients, with particular emphasis on the risk factors of recurrence together with treatment outcomes. Subjects and Methods: Between January 2000 and July 2018, patients <20 years who were diagnosed with thyroid carcinoma and primarily treated with surgery at a major large-volume tertiary medical center specializing in thyroid cancer were enrolled. A total of 83 patients were eligible for this study. Results: The majority of the studied patients were girls and adolescents (age ≥13 years). Papillary thyroid carcinoma (PTC) was the most common pathology (n = 74). PTC tumors >1 cm showed higher rate of lymph node metastasis and extrathyroidal extension than tumors ≤1 cm. All patients survived with nine PTC patients who displayed treatment failure. Age, tumor size, multifocality, lateral lymph node metastasis, and postoperative thyroglobulin levels were significant prognosticators for disease recurrence. Conclusion: Pediatric thyroid cancer is relatively rare and should be considered a specific disease entity with respect to the thyroid cancer in adults, since there are several distinctive characteristics.

Original languageEnglish
JournalAnnals of Otology, Rhinology and Laryngology
DOIs
Publication statusPublished - 2019 Jan 1

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Thyroid Neoplasms
Pediatrics
Lymph Nodes
Neoplasm Metastasis
Recurrence
Factor IX
Thyroglobulin
Treatment Failure
Neoplasms
Incidence

Keywords

  • papillary thyroid carcinoma
  • pediatric thyroid cancer
  • recurrence

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Clinical Analysis of Pediatric Thyroid Cancer : A Single Medical Institution Experience of 18 Years. / Byeon, Hyung Kwon; Kim, Sang Bin; Oh, Hyeon Seok; Kim, Hong Kyu; Choi, In Hak; Kim, Hyunjung; Cho, Jae Gu; Oh, Kyung Ho; Baek, Seung Kuk; Woo, Jeong Soo; Kwon, Soon Young; Kim, Hoon Yub; Jung, Kwang Yoon.

In: Annals of Otology, Rhinology and Laryngology, 01.01.2019.

Research output: Contribution to journalArticle

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