Clinical and temperamental differences between early- and late-onset alcoholism in Korean men

Se Won Lim, Kang Seob Oh, Young Chul Shin, Seung Gul Kang, Leen Kim, Young Min Park, Won Kim, Heon-Jeong Lee

Research output: Contribution to journalArticle

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Abstract

Objectives: The aims of this study were to elucidate the clinical and temperamental differences between early- and late-onset alcoholism among Korean men and to ascertain the validity of Cloninger's typology model of alcoholism for Koreans. Methods: All of the subjects were screened after a detoxification period of at least 2 weeks using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders for diagnosing alcohol dependence and identifying psychiatric comorbidities. The Korean version of the tridimensional personality questionnaire was then administered to 173 male alcoholic inpatients; and information regarding their criminality, family history of alcoholism, and age at the onset of alcohol-related problems was gathered. We divided the patients into 2 groups based on the age at the onset of alcoholism: (1) early onset (n = 80), when they were up to 25 years old at the onset, and (2) late onset (n = 93), when they were older than 25 years at the onset. Results: Early-onset patients exhibited more criminality (χ 2 = 15.45, df = 1, P < .001, odds ratio [OR] = 3.84, 95% confidence interval [CI] = 1.93-7.65), suicide attempts (χ 2 = 7.92, df = 1, P = .005, OR [95% CI] = 3.14 [1.38-7.15]), and family history of alcoholism (χ 2 = 24.75, df = 1, P < .001, OR [95% CI] = 5.27 [2.67-10.37]). With regard to the tridimensional personality questionnaire profile, the early-onset patients exhibited a higher score of novelty seeking (t = 3.42, P = .001), with the difference still being significant after adjusting for age by analysis of covariance (using age as a covariate) (F = 5.928, P = .016). However, harm avoidance (t = -0.13, P = .89), reward dependence (t = -0.19, P = .85), and persistence (t = -0.62, P = .54) did not differ between the 2 groups. Conclusions: There were several distinct clinical and temperamental differences between early- and late-onset alcoholism among Korean male alcoholic patients. It is suggested that the age at the onset of alcoholism can be used to discriminate alcoholic subtypes. Our data also partly support Cloninger's typology of 2 types of alcoholic individuals.

Original languageEnglish
Pages (from-to)94-97
Number of pages4
JournalComprehensive Psychiatry
Volume49
Issue number1
DOIs
Publication statusPublished - 2008 Jan 1

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Alcoholism
Age of Onset
Odds Ratio
Confidence Intervals
Alcoholics
Personality
Reward
Diagnostic and Statistical Manual of Mental Disorders
Suicide
Psychiatry
Comorbidity
Inpatients
Alcohols
Interviews

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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Clinical and temperamental differences between early- and late-onset alcoholism in Korean men. / Lim, Se Won; Oh, Kang Seob; Shin, Young Chul; Kang, Seung Gul; Kim, Leen; Park, Young Min; Kim, Won; Lee, Heon-Jeong.

In: Comprehensive Psychiatry, Vol. 49, No. 1, 01.01.2008, p. 94-97.

Research output: Contribution to journalArticle

Lim, Se Won ; Oh, Kang Seob ; Shin, Young Chul ; Kang, Seung Gul ; Kim, Leen ; Park, Young Min ; Kim, Won ; Lee, Heon-Jeong. / Clinical and temperamental differences between early- and late-onset alcoholism in Korean men. In: Comprehensive Psychiatry. 2008 ; Vol. 49, No. 1. pp. 94-97.
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abstract = "Objectives: The aims of this study were to elucidate the clinical and temperamental differences between early- and late-onset alcoholism among Korean men and to ascertain the validity of Cloninger's typology model of alcoholism for Koreans. Methods: All of the subjects were screened after a detoxification period of at least 2 weeks using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders for diagnosing alcohol dependence and identifying psychiatric comorbidities. The Korean version of the tridimensional personality questionnaire was then administered to 173 male alcoholic inpatients; and information regarding their criminality, family history of alcoholism, and age at the onset of alcohol-related problems was gathered. We divided the patients into 2 groups based on the age at the onset of alcoholism: (1) early onset (n = 80), when they were up to 25 years old at the onset, and (2) late onset (n = 93), when they were older than 25 years at the onset. Results: Early-onset patients exhibited more criminality (χ 2 = 15.45, df = 1, P < .001, odds ratio [OR] = 3.84, 95{\%} confidence interval [CI] = 1.93-7.65), suicide attempts (χ 2 = 7.92, df = 1, P = .005, OR [95{\%} CI] = 3.14 [1.38-7.15]), and family history of alcoholism (χ 2 = 24.75, df = 1, P < .001, OR [95{\%} CI] = 5.27 [2.67-10.37]). With regard to the tridimensional personality questionnaire profile, the early-onset patients exhibited a higher score of novelty seeking (t = 3.42, P = .001), with the difference still being significant after adjusting for age by analysis of covariance (using age as a covariate) (F = 5.928, P = .016). However, harm avoidance (t = -0.13, P = .89), reward dependence (t = -0.19, P = .85), and persistence (t = -0.62, P = .54) did not differ between the 2 groups. Conclusions: There were several distinct clinical and temperamental differences between early- and late-onset alcoholism among Korean male alcoholic patients. It is suggested that the age at the onset of alcoholism can be used to discriminate alcoholic subtypes. Our data also partly support Cloninger's typology of 2 types of alcoholic individuals.",
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AU - Shin, Young Chul

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AU - Kim, Leen

AU - Park, Young Min

AU - Kim, Won

AU - Lee, Heon-Jeong

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N2 - Objectives: The aims of this study were to elucidate the clinical and temperamental differences between early- and late-onset alcoholism among Korean men and to ascertain the validity of Cloninger's typology model of alcoholism for Koreans. Methods: All of the subjects were screened after a detoxification period of at least 2 weeks using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I Disorders for diagnosing alcohol dependence and identifying psychiatric comorbidities. The Korean version of the tridimensional personality questionnaire was then administered to 173 male alcoholic inpatients; and information regarding their criminality, family history of alcoholism, and age at the onset of alcohol-related problems was gathered. We divided the patients into 2 groups based on the age at the onset of alcoholism: (1) early onset (n = 80), when they were up to 25 years old at the onset, and (2) late onset (n = 93), when they were older than 25 years at the onset. Results: Early-onset patients exhibited more criminality (χ 2 = 15.45, df = 1, P < .001, odds ratio [OR] = 3.84, 95% confidence interval [CI] = 1.93-7.65), suicide attempts (χ 2 = 7.92, df = 1, P = .005, OR [95% CI] = 3.14 [1.38-7.15]), and family history of alcoholism (χ 2 = 24.75, df = 1, P < .001, OR [95% CI] = 5.27 [2.67-10.37]). With regard to the tridimensional personality questionnaire profile, the early-onset patients exhibited a higher score of novelty seeking (t = 3.42, P = .001), with the difference still being significant after adjusting for age by analysis of covariance (using age as a covariate) (F = 5.928, P = .016). However, harm avoidance (t = -0.13, P = .89), reward dependence (t = -0.19, P = .85), and persistence (t = -0.62, P = .54) did not differ between the 2 groups. Conclusions: There were several distinct clinical and temperamental differences between early- and late-onset alcoholism among Korean male alcoholic patients. It is suggested that the age at the onset of alcoholism can be used to discriminate alcoholic subtypes. Our data also partly support Cloninger's typology of 2 types of alcoholic individuals.

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