Clinical characteristics of smoking asthmatics

Sil H. Eun, Ok Kim Hye, Ju Lee Kyoung, Eun Joo Lee, Gyu Young Hur, Hwan Jung Ki, Sung Yong Lee, Je Hyeong Kim, Sang Yeub Lee, Chol Shin, Jae Jeong Shim, Ho Kang Kyung, Hwa Yoo Se, Kwang Ho In

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second (FEV1) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean FEV1 (% predicted) was 76.8±19.8%, 71.6±21.1% and 87.9±18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The FEV1/forced vital capacity (FVC) (ratio, %) values were 63.6±12.6%, 59.3±14.9% and 72.1±11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual FEV1 slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients. Copyright

Original languageEnglish
Pages (from-to)506-511
Number of pages6
JournalTuberculosis and Respiratory Diseases
Volume67
Issue number6
DOIs
Publication statusPublished - 2009 Dec 1

Fingerprint

Smoking
History
Lung
Asthma
Vital Capacity
Forced Expiratory Volume
Medical Records
Population

Keywords

  • Asthma
  • Diseases progression
  • Respiratory function tests
  • Smoking

ASJC Scopus subject areas

  • Infectious Diseases
  • Pulmonary and Respiratory Medicine

Cite this

Clinical characteristics of smoking asthmatics. / Eun, Sil H.; Hye, Ok Kim; Kyoung, Ju Lee; Lee, Eun Joo; Hur, Gyu Young; Ki, Hwan Jung; Lee, Sung Yong; Kim, Je Hyeong; Lee, Sang Yeub; Shin, Chol; Shim, Jae Jeong; Kyung, Ho Kang; Se, Hwa Yoo; In, Kwang Ho.

In: Tuberculosis and Respiratory Diseases, Vol. 67, No. 6, 01.12.2009, p. 506-511.

Research output: Contribution to journalArticle

@article{1f37fd7fc4364542b1d9a24e8cd1de1b,
title = "Clinical characteristics of smoking asthmatics",
abstract = "Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second (FEV1) were compared. Results: Fifty-three of the 142 patients (37{\%}) were current smokers, 24 were former smokers (17{\%}) and 65 were non-smokers (45{\%}). The patients with a hospital admission history during the previous year included 16 current smokers (30{\%}), 4 former smokers (17{\%}) and 7 non-smokers (11{\%}) (p=0.02). The mean FEV1 ({\%} predicted) was 76.8±19.8{\%}, 71.6±21.1{\%} and 87.9±18.7{\%} for current smokers, former smokers and non-smokers, respectively (p< 0.001). The FEV1/forced vital capacity (FVC) (ratio, {\%}) values were 63.6±12.6{\%}, 59.3±14.9{\%} and 72.1±11.8{\%} in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual FEV1 slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients. Copyright",
keywords = "Asthma, Diseases progression, Respiratory function tests, Smoking",
author = "Eun, {Sil H.} and Hye, {Ok Kim} and Kyoung, {Ju Lee} and Lee, {Eun Joo} and Hur, {Gyu Young} and Ki, {Hwan Jung} and Lee, {Sung Yong} and Kim, {Je Hyeong} and Lee, {Sang Yeub} and Chol Shin and Shim, {Jae Jeong} and Kyung, {Ho Kang} and Se, {Hwa Yoo} and In, {Kwang Ho}",
year = "2009",
month = "12",
day = "1",
doi = "10.4046/trd.2009.67.6.506",
language = "English",
volume = "67",
pages = "506--511",
journal = "Tuberculosis and Respiratory Diseases",
issn = "1738-3536",
publisher = "The Korean Academy of Tuberculosis and Respiratory Diseases",
number = "6",

}

TY - JOUR

T1 - Clinical characteristics of smoking asthmatics

AU - Eun, Sil H.

AU - Hye, Ok Kim

AU - Kyoung, Ju Lee

AU - Lee, Eun Joo

AU - Hur, Gyu Young

AU - Ki, Hwan Jung

AU - Lee, Sung Yong

AU - Kim, Je Hyeong

AU - Lee, Sang Yeub

AU - Shin, Chol

AU - Shim, Jae Jeong

AU - Kyung, Ho Kang

AU - Se, Hwa Yoo

AU - In, Kwang Ho

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second (FEV1) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean FEV1 (% predicted) was 76.8±19.8%, 71.6±21.1% and 87.9±18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The FEV1/forced vital capacity (FVC) (ratio, %) values were 63.6±12.6%, 59.3±14.9% and 72.1±11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual FEV1 slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients. Copyright

AB - Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second (FEV1) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean FEV1 (% predicted) was 76.8±19.8%, 71.6±21.1% and 87.9±18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The FEV1/forced vital capacity (FVC) (ratio, %) values were 63.6±12.6%, 59.3±14.9% and 72.1±11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual FEV1 slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients. Copyright

KW - Asthma

KW - Diseases progression

KW - Respiratory function tests

KW - Smoking

UR - http://www.scopus.com/inward/record.url?scp=76049107844&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76049107844&partnerID=8YFLogxK

U2 - 10.4046/trd.2009.67.6.506

DO - 10.4046/trd.2009.67.6.506

M3 - Article

AN - SCOPUS:76049107844

VL - 67

SP - 506

EP - 511

JO - Tuberculosis and Respiratory Diseases

JF - Tuberculosis and Respiratory Diseases

SN - 1738-3536

IS - 6

ER -