Clinical features and survival outcomes in patients with multiple myeloma: Analysis of web-based data from the korean myeloma registry

Seok Jin Kim, Kihyun Kim, Byung Soo Kim, Deog Yeon Jo, Hye Jin Kang, Jin Seok Kim, Yeung Chul Mun, Chul Soo Kim, Sang Kyun Sohn, Hyeon Seok Eom, Jae Yong Kwak, Hyeok Shim, Hwi Joong Yoon, Jong Youl Jin, Chang Ki Min, Hyunchoon Shin, Jong Ho Won, Je Jung Lee, Jung Hye Kwon, Young Don JooYoung Rok Do, Sung Hyun Kim, Sukjoong Oh, Cheolwon Suh, Junglim Lee, Sung Soo Yoon, Min Kyoung Kim, Soo Mee Bang, Hun Mo Ryoo, Bong Seog Kim, Hawk Kim, Hyo Jung Kim, Yang Soo Kim, Chong Won Park, Gyeong Won Lee, Ho Jin Shin, Seong Kyu Park, Joon Seong Park, Ho Young Kim, Dong Soon Lee, Jae Hoon Lee

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Aim: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. Methods: We retrospectively analyzed registered data from 3,209 patients since 1999. Results: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20-54.06 months). Patients ≤40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. Conclusions: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.

Original languageEnglish
Pages (from-to)200-210
Number of pages11
JournalActa Haematologica
Volume122
Issue number4
DOIs
Publication statusPublished - 2009 Nov 1

Keywords

  • Multiple myeloma
  • Stem cell transplantation, autologous
  • Stem cell transplantation, tandem autologous

ASJC Scopus subject areas

  • Hematology

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    Kim, S. J., Kim, K., Kim, B. S., Jo, D. Y., Kang, H. J., Kim, J. S., Mun, Y. C., Kim, C. S., Sohn, S. K., Eom, H. S., Kwak, J. Y., Shim, H., Yoon, H. J., Jin, J. Y., Min, C. K., Shin, H., Won, J. H., Lee, J. J., Kwon, J. H., ... Lee, J. H. (2009). Clinical features and survival outcomes in patients with multiple myeloma: Analysis of web-based data from the korean myeloma registry. Acta Haematologica, 122(4), 200-210. https://doi.org/10.1159/000253027