Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Korea: A Prospective, Observational, Cohort Study

Woo Joo Kim, Jin Soo Lee, Chang Kyu Lee, Hee-Jin Cheong, Mijeong Kim, Javier Sawchik Monegal, Rute Carneiro, Moe H. Kyaw, Haguinet François Haguinet, Riju Ray, Gonçalo Matias

Research output: Contribution to journalArticle


Two prospective, multi-centre, observational studies (GlaxoSmithKline [GSK] identifier No. 110938 and 112519) were performed over 2 influenza seasons (2007-2008 and 2008-2009) in the Republic of Korea (ROK) with the aim to evaluate the burden of laboratoryconfirmed influenza (LCI) in patients = 50 years of age seeking medical attention for acute respiratory illness (ARI). The median participant age was 58 years in the 2007-2008 season and 60 years in the 2008-2009 season. LCI was observed in 101/346 (29.2%) of ARI patients in the 2007-2008 season and in 166/443 (37.5%) of ARI patients in the 2008- 2009 season. Compared to patients with non-influenza ARI, those with LCI had higher rates of decreased daily activities (60.4% vs. 32.9% in 2007-2008 and 46.4% vs. 25.8% in 2008-2009), work absenteeism (51.1% vs. 25.6% and 14.4% vs. 7.7%), and longer duration of illness. These results indicated that influenza is an important cause of ARI in adults aged 50 and older causing more severe illness than non-influenza related ARI.

Original languageEnglish
Pages (from-to)407-414
Number of pages8
JournalJournal of Korean Medical Science
Issue number3
Publication statusPublished - 2017



  • Acute Respiratory Illness
  • Adult
  • Epidemiology
  • Influenza
  • Republic of Korea

ASJC Scopus subject areas

  • Medicine(all)

Cite this