Clinical features of probable cluster headache: A prospective, cross-sectional multicenter study

Jong Hee Sohn, Yun Ju Choi, Byung Kun Kim, Pil Wook Chung, Mi Ji Lee, Min Kyung Chu, Jin Young Ahn, Byung Su Kim, Tae Jin Song, Kyungmi Oh, Kwang Soo Lee, Soo Kyoung Kim, Kwang Yeol Park, Jae Myun Chung, Heui Soo Moon, Chin Sang Chung, Soo Jin Cho, Jeong Wook Park

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Epidemiological data of probable cluster headaches (CH) are scarce in the relevant literature. Here, we sought to assess the prevalence and clinical characteristics of probable CH in comparison with definite CH. Methods: Data used in this study were obtained from the Korean Cluster Headache Registry (KCHR), a prospective, cross-sectional, multicenter headache registry that collected data from consecutive patients diagnosed with CH. Results: In total, 159 patients were enrolled in this study; 20 (12.6%) were diagnosed with probable CH. The most common unfulfilled criterion in patients with probable CH was the duration of attack, which was found in 40% of patients with probable CH. Among clinical characteristics, the number of autonomic symptoms tended to be lower in probable CH than in definite CH (1.7 ± 1.2 vs. 2.4 ± 1.5, p = 0.051) and conjunctival injection and lacrimation showed an increased odds ratio (OR) [OR = 3.03; 95% confidence interval (CI): 1.03-8.33] in definite CH. The groups did not differ with regard to baseline demographic characteristics, disability, impact on life, or treatment response. Conclusions: Probable CH is relatively common among CH disorders, with a clinical impact similar to that of definite CH.

Original languageEnglish
JournalFrontiers in Neurology
Volume9
Issue numberOCT
DOIs
Publication statusPublished - 2018 Oct 26

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Cluster Headache
Multicenter Studies
Cross-Sectional Studies
Registries
Odds Ratio
Headache Disorders

Keywords

  • Autonomic symptom
  • Cluster headache
  • Definite diagnosis
  • Probable diagnosis
  • Trigeminal autonomic cephalalgia

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Sohn, J. H., Choi, Y. J., Kim, B. K., Chung, P. W., Lee, M. J., Chu, M. K., ... Park, J. W. (2018). Clinical features of probable cluster headache: A prospective, cross-sectional multicenter study. Frontiers in Neurology, 9(OCT). https://doi.org/10.3389/fneur.2018.00908

Clinical features of probable cluster headache : A prospective, cross-sectional multicenter study. / Sohn, Jong Hee; Choi, Yun Ju; Kim, Byung Kun; Chung, Pil Wook; Lee, Mi Ji; Chu, Min Kyung; Ahn, Jin Young; Kim, Byung Su; Song, Tae Jin; Oh, Kyungmi; Lee, Kwang Soo; Kim, Soo Kyoung; Park, Kwang Yeol; Chung, Jae Myun; Moon, Heui Soo; Chung, Chin Sang; Cho, Soo Jin; Park, Jeong Wook.

In: Frontiers in Neurology, Vol. 9, No. OCT, 26.10.2018.

Research output: Contribution to journalArticle

Sohn, JH, Choi, YJ, Kim, BK, Chung, PW, Lee, MJ, Chu, MK, Ahn, JY, Kim, BS, Song, TJ, Oh, K, Lee, KS, Kim, SK, Park, KY, Chung, JM, Moon, HS, Chung, CS, Cho, SJ & Park, JW 2018, 'Clinical features of probable cluster headache: A prospective, cross-sectional multicenter study', Frontiers in Neurology, vol. 9, no. OCT. https://doi.org/10.3389/fneur.2018.00908
Sohn, Jong Hee ; Choi, Yun Ju ; Kim, Byung Kun ; Chung, Pil Wook ; Lee, Mi Ji ; Chu, Min Kyung ; Ahn, Jin Young ; Kim, Byung Su ; Song, Tae Jin ; Oh, Kyungmi ; Lee, Kwang Soo ; Kim, Soo Kyoung ; Park, Kwang Yeol ; Chung, Jae Myun ; Moon, Heui Soo ; Chung, Chin Sang ; Cho, Soo Jin ; Park, Jeong Wook. / Clinical features of probable cluster headache : A prospective, cross-sectional multicenter study. In: Frontiers in Neurology. 2018 ; Vol. 9, No. OCT.
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abstract = "Background: Epidemiological data of probable cluster headaches (CH) are scarce in the relevant literature. Here, we sought to assess the prevalence and clinical characteristics of probable CH in comparison with definite CH. Methods: Data used in this study were obtained from the Korean Cluster Headache Registry (KCHR), a prospective, cross-sectional, multicenter headache registry that collected data from consecutive patients diagnosed with CH. Results: In total, 159 patients were enrolled in this study; 20 (12.6{\%}) were diagnosed with probable CH. The most common unfulfilled criterion in patients with probable CH was the duration of attack, which was found in 40{\%} of patients with probable CH. Among clinical characteristics, the number of autonomic symptoms tended to be lower in probable CH than in definite CH (1.7 ± 1.2 vs. 2.4 ± 1.5, p = 0.051) and conjunctival injection and lacrimation showed an increased odds ratio (OR) [OR = 3.03; 95{\%} confidence interval (CI): 1.03-8.33] in definite CH. The groups did not differ with regard to baseline demographic characteristics, disability, impact on life, or treatment response. Conclusions: Probable CH is relatively common among CH disorders, with a clinical impact similar to that of definite CH.",
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AU - Sohn, Jong Hee

AU - Choi, Yun Ju

AU - Kim, Byung Kun

AU - Chung, Pil Wook

AU - Lee, Mi Ji

AU - Chu, Min Kyung

AU - Ahn, Jin Young

AU - Kim, Byung Su

AU - Song, Tae Jin

AU - Oh, Kyungmi

AU - Lee, Kwang Soo

AU - Kim, Soo Kyoung

AU - Park, Kwang Yeol

AU - Chung, Jae Myun

AU - Moon, Heui Soo

AU - Chung, Chin Sang

AU - Cho, Soo Jin

AU - Park, Jeong Wook

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Y1 - 2018/10/26

N2 - Background: Epidemiological data of probable cluster headaches (CH) are scarce in the relevant literature. Here, we sought to assess the prevalence and clinical characteristics of probable CH in comparison with definite CH. Methods: Data used in this study were obtained from the Korean Cluster Headache Registry (KCHR), a prospective, cross-sectional, multicenter headache registry that collected data from consecutive patients diagnosed with CH. Results: In total, 159 patients were enrolled in this study; 20 (12.6%) were diagnosed with probable CH. The most common unfulfilled criterion in patients with probable CH was the duration of attack, which was found in 40% of patients with probable CH. Among clinical characteristics, the number of autonomic symptoms tended to be lower in probable CH than in definite CH (1.7 ± 1.2 vs. 2.4 ± 1.5, p = 0.051) and conjunctival injection and lacrimation showed an increased odds ratio (OR) [OR = 3.03; 95% confidence interval (CI): 1.03-8.33] in definite CH. The groups did not differ with regard to baseline demographic characteristics, disability, impact on life, or treatment response. Conclusions: Probable CH is relatively common among CH disorders, with a clinical impact similar to that of definite CH.

AB - Background: Epidemiological data of probable cluster headaches (CH) are scarce in the relevant literature. Here, we sought to assess the prevalence and clinical characteristics of probable CH in comparison with definite CH. Methods: Data used in this study were obtained from the Korean Cluster Headache Registry (KCHR), a prospective, cross-sectional, multicenter headache registry that collected data from consecutive patients diagnosed with CH. Results: In total, 159 patients were enrolled in this study; 20 (12.6%) were diagnosed with probable CH. The most common unfulfilled criterion in patients with probable CH was the duration of attack, which was found in 40% of patients with probable CH. Among clinical characteristics, the number of autonomic symptoms tended to be lower in probable CH than in definite CH (1.7 ± 1.2 vs. 2.4 ± 1.5, p = 0.051) and conjunctival injection and lacrimation showed an increased odds ratio (OR) [OR = 3.03; 95% confidence interval (CI): 1.03-8.33] in definite CH. The groups did not differ with regard to baseline demographic characteristics, disability, impact on life, or treatment response. Conclusions: Probable CH is relatively common among CH disorders, with a clinical impact similar to that of definite CH.

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