Clinical significance of small colorectal adenoma less than 10mm: The KASID study

Woo Yoo Tae, Il Park Dong, Young Ho Kim, Soo Kim Hyun, Ho Kim Won, Il Kim Tae, Jong Kim Hyo, Suk Kyun Yang, Jeong Sik Byeon, Sung Lee Moon, Kwon Jung Il, Kwan Chung Moon, Sung Ae Jung, Yoon Tae Jeen, Hyun Choi Jai, Hwang Choi, Soo Han Dong, Suk Song Jae

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Abstract

Background/Aims: Polypectomy is the current modality of choice to prevent benign colorectal adenoma from progressing to an invasive cancer. However, in cases of small colorectal adenoma, it remains unclear as to whether polypectomy is actually an effective treatment modality. We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10mm. Methodology: All colonoscopies were performed at 11 Korean tertiary medical centers, between July 2003 and March 2004. A total of 5,996 colorectal adenomas were detected and divided into 5 groups according to their size (Group 1; 1-5mm, Group 2; 6-7mm, Group 3; 8-9mm, Group 4; 10-19mm, Group 5; more than 20mm). The term 'advanced adenoma' refers here to tubular adenomas with diameters of at least 10mm, or to tubulovillous, villous, or high-grade dysplasia, irrespective of size. 'Cancer' here is defined as the invasion of malignant cells beyond the muscularis mucosa. Results: As the sizes of the adenomas increased, the prevalence of advanced adenoma was also observed to increase. In Groups 2 and 3, the prevalence of tubulovillous or villous adenoma were higher than was expected (5.2% and 6.6%, p <0.001). Interestingly enough, in Group 2, the prevalence of cancer was at least as high as in Group 4 (0.7% vs. 0.5%, p <0.001). Conclusions: In cases of small colorectal adenomas, measuring between 6 and 9mm, the prevalence of cancer was at least as high as that seen in the cases of colorectal adenomas measuring between 10 and 19mm. Therefore, small colorectal adenomas measuring between 6 and 9mm should not be ignored, in order to decrease the prevalence of colorectal cancer.

Original languageEnglish
Pages (from-to)418-421
Number of pages4
JournalHepato-Gastroenterology
Volume54
Issue number74
Publication statusPublished - 2007 Mar 1

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Adenoma
Neoplasms
Villous Adenoma
Colonoscopy
Colorectal Neoplasms
Mucous Membrane

Keywords

  • Advanced adenoma
  • Colorectal cancer
  • Small colorectal adenoma

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Tae, W. Y., Dong, I. P., Kim, Y. H., Hyun, S. K., Won, H. K., Tae, I. K., ... Jae, S. S. (2007). Clinical significance of small colorectal adenoma less than 10mm: The KASID study. Hepato-Gastroenterology, 54(74), 418-421.

Clinical significance of small colorectal adenoma less than 10mm : The KASID study. / Tae, Woo Yoo; Dong, Il Park; Kim, Young Ho; Hyun, Soo Kim; Won, Ho Kim; Tae, Il Kim; Hyo, Jong Kim; Yang, Suk Kyun; Byeon, Jeong Sik; Moon, Sung Lee; Il, Kwon Jung; Moon, Kwan Chung; Jung, Sung Ae; Jeen, Yoon Tae; Jai, Hyun Choi; Choi, Hwang; Dong, Soo Han; Jae, Suk Song.

In: Hepato-Gastroenterology, Vol. 54, No. 74, 01.03.2007, p. 418-421.

Research output: Contribution to journalArticle

Tae, WY, Dong, IP, Kim, YH, Hyun, SK, Won, HK, Tae, IK, Hyo, JK, Yang, SK, Byeon, JS, Moon, SL, Il, KJ, Moon, KC, Jung, SA, Jeen, YT, Jai, HC, Choi, H, Dong, SH & Jae, SS 2007, 'Clinical significance of small colorectal adenoma less than 10mm: The KASID study', Hepato-Gastroenterology, vol. 54, no. 74, pp. 418-421.
Tae WY, Dong IP, Kim YH, Hyun SK, Won HK, Tae IK et al. Clinical significance of small colorectal adenoma less than 10mm: The KASID study. Hepato-Gastroenterology. 2007 Mar 1;54(74):418-421.
Tae, Woo Yoo ; Dong, Il Park ; Kim, Young Ho ; Hyun, Soo Kim ; Won, Ho Kim ; Tae, Il Kim ; Hyo, Jong Kim ; Yang, Suk Kyun ; Byeon, Jeong Sik ; Moon, Sung Lee ; Il, Kwon Jung ; Moon, Kwan Chung ; Jung, Sung Ae ; Jeen, Yoon Tae ; Jai, Hyun Choi ; Choi, Hwang ; Dong, Soo Han ; Jae, Suk Song. / Clinical significance of small colorectal adenoma less than 10mm : The KASID study. In: Hepato-Gastroenterology. 2007 ; Vol. 54, No. 74. pp. 418-421.
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abstract = "Background/Aims: Polypectomy is the current modality of choice to prevent benign colorectal adenoma from progressing to an invasive cancer. However, in cases of small colorectal adenoma, it remains unclear as to whether polypectomy is actually an effective treatment modality. We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10mm. Methodology: All colonoscopies were performed at 11 Korean tertiary medical centers, between July 2003 and March 2004. A total of 5,996 colorectal adenomas were detected and divided into 5 groups according to their size (Group 1; 1-5mm, Group 2; 6-7mm, Group 3; 8-9mm, Group 4; 10-19mm, Group 5; more than 20mm). The term 'advanced adenoma' refers here to tubular adenomas with diameters of at least 10mm, or to tubulovillous, villous, or high-grade dysplasia, irrespective of size. 'Cancer' here is defined as the invasion of malignant cells beyond the muscularis mucosa. Results: As the sizes of the adenomas increased, the prevalence of advanced adenoma was also observed to increase. In Groups 2 and 3, the prevalence of tubulovillous or villous adenoma were higher than was expected (5.2{\%} and 6.6{\%}, p <0.001). Interestingly enough, in Group 2, the prevalence of cancer was at least as high as in Group 4 (0.7{\%} vs. 0.5{\%}, p <0.001). Conclusions: In cases of small colorectal adenomas, measuring between 6 and 9mm, the prevalence of cancer was at least as high as that seen in the cases of colorectal adenomas measuring between 10 and 19mm. Therefore, small colorectal adenomas measuring between 6 and 9mm should not be ignored, in order to decrease the prevalence of colorectal cancer.",
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T1 - Clinical significance of small colorectal adenoma less than 10mm

T2 - The KASID study

AU - Tae, Woo Yoo

AU - Dong, Il Park

AU - Kim, Young Ho

AU - Hyun, Soo Kim

AU - Won, Ho Kim

AU - Tae, Il Kim

AU - Hyo, Jong Kim

AU - Yang, Suk Kyun

AU - Byeon, Jeong Sik

AU - Moon, Sung Lee

AU - Il, Kwon Jung

AU - Moon, Kwan Chung

AU - Jung, Sung Ae

AU - Jeen, Yoon Tae

AU - Jai, Hyun Choi

AU - Choi, Hwang

AU - Dong, Soo Han

AU - Jae, Suk Song

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Background/Aims: Polypectomy is the current modality of choice to prevent benign colorectal adenoma from progressing to an invasive cancer. However, in cases of small colorectal adenoma, it remains unclear as to whether polypectomy is actually an effective treatment modality. We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10mm. Methodology: All colonoscopies were performed at 11 Korean tertiary medical centers, between July 2003 and March 2004. A total of 5,996 colorectal adenomas were detected and divided into 5 groups according to their size (Group 1; 1-5mm, Group 2; 6-7mm, Group 3; 8-9mm, Group 4; 10-19mm, Group 5; more than 20mm). The term 'advanced adenoma' refers here to tubular adenomas with diameters of at least 10mm, or to tubulovillous, villous, or high-grade dysplasia, irrespective of size. 'Cancer' here is defined as the invasion of malignant cells beyond the muscularis mucosa. Results: As the sizes of the adenomas increased, the prevalence of advanced adenoma was also observed to increase. In Groups 2 and 3, the prevalence of tubulovillous or villous adenoma were higher than was expected (5.2% and 6.6%, p <0.001). Interestingly enough, in Group 2, the prevalence of cancer was at least as high as in Group 4 (0.7% vs. 0.5%, p <0.001). Conclusions: In cases of small colorectal adenomas, measuring between 6 and 9mm, the prevalence of cancer was at least as high as that seen in the cases of colorectal adenomas measuring between 10 and 19mm. Therefore, small colorectal adenomas measuring between 6 and 9mm should not be ignored, in order to decrease the prevalence of colorectal cancer.

AB - Background/Aims: Polypectomy is the current modality of choice to prevent benign colorectal adenoma from progressing to an invasive cancer. However, in cases of small colorectal adenoma, it remains unclear as to whether polypectomy is actually an effective treatment modality. We evaluated the clinical significance of polypectomy in cases of small colorectal adenomas, measuring less than 10mm. Methodology: All colonoscopies were performed at 11 Korean tertiary medical centers, between July 2003 and March 2004. A total of 5,996 colorectal adenomas were detected and divided into 5 groups according to their size (Group 1; 1-5mm, Group 2; 6-7mm, Group 3; 8-9mm, Group 4; 10-19mm, Group 5; more than 20mm). The term 'advanced adenoma' refers here to tubular adenomas with diameters of at least 10mm, or to tubulovillous, villous, or high-grade dysplasia, irrespective of size. 'Cancer' here is defined as the invasion of malignant cells beyond the muscularis mucosa. Results: As the sizes of the adenomas increased, the prevalence of advanced adenoma was also observed to increase. In Groups 2 and 3, the prevalence of tubulovillous or villous adenoma were higher than was expected (5.2% and 6.6%, p <0.001). Interestingly enough, in Group 2, the prevalence of cancer was at least as high as in Group 4 (0.7% vs. 0.5%, p <0.001). Conclusions: In cases of small colorectal adenomas, measuring between 6 and 9mm, the prevalence of cancer was at least as high as that seen in the cases of colorectal adenomas measuring between 10 and 19mm. Therefore, small colorectal adenomas measuring between 6 and 9mm should not be ignored, in order to decrease the prevalence of colorectal cancer.

KW - Advanced adenoma

KW - Colorectal cancer

KW - Small colorectal adenoma

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