Clinical validation of the psychotic depression assessment scale, hamilton depression rating scale-6, and brief psychiatric rating scale-5: Results from the clinical research center for depression study

Seon Cheol Park, Eun Young Jang, Jae Min Kim, Tae Youn Jun, Min-Soo Lee, Jung Bum Kim, Hyeon Woo Yim, Yong Chon Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, were analyzed. Methods Fifty-two patients with psychotic depression from the CRESCEND study met our inclusion criteria. The patients underwent the following psychometric assessments: the PDAS, including HAMD-6 and BPRS-5, the clinical global impression scales, the HAMD, the positive symptom subscale, and the negative symptom subscale. Assessments were performed at the baseline and then at weeks 1, 2, 4, 8, 12, 24, and 52. Spearman correlation analyses were used to assess the clinical validity and responsiveness of the PDAS. Results The clinical validity and responsiveness of the PDAS, including HAMD-6 and BPRS-5, were acceptable, with the exception of the clinical responsiveness of the PDAS for positive symptoms and the clinical responsiveness of BPRS-5 for negative symptoms. Conclusion The clinical relevance of the PDAS has been confirmed and this clinical validation will enhance its clinical utility and availability.

Original languageEnglish
Pages (from-to)568-576
Number of pages9
JournalPsychiatry Investigation
Volume14
Issue number5
DOIs
Publication statusPublished - 2017 Sep 1

Keywords

  • 5-item psychosis subscale
  • 6-item melancholia subscale
  • Clinical validation
  • Psychotic depression
  • Psychotic depression assessment scale

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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