Abstract
This paper demonstrates the utility of coextrusion-based 3D plotting of ceramic pastes (CoEx-3DP) as a new type of additive manufacturing (AM) technique, which can produce porous calcium phosphate (CaP) ceramic scaffolds comprised of hollow CaP filaments. In this technique, green filaments with a controlled core/shell structure can be produced by coextruding an initial feedrod, comprised of the carbon black (CB) core and CaP shell, through a fine nozzle in an acetone bath and then deposited in a controlled manner according to predetermined paths. In addition, channels in CaP filaments can be created through the removal of the CB cores during heat-treatment. Produced CaP scaffolds had two different types of pores with well-defined geometries: three-dimensionally interconnected pores (~360 × 230 μm2 in sizes) and channels (> 100 μm in diameter) in hollow CaP filaments. The porous scaffolds showed high compressive strengths of ~12.3 ± 2.2 MPa at a high porosity of ~73 vol % when compressed parallel to the direction of the hollow CaP filaments. In addition, the mechanical properties of porous CaP scaffolds could be tailored by adjusting their porosity, for example, compressive strengths of 4.8 ± 1.1 MPa at a porosity of ~82 vol %. The porous CaP scaffold showed good biocompatibility, which was assessed by in vitro cell tests, where several the cells adhered to and spread actively with the outer and inner surfaces of the hollow CaP filaments.
| Original language | English |
|---|---|
| Article number | 911 |
| Journal | Materials |
| Volume | 11 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2018 May 29 |
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Keywords
- Additive manufacturing
- Biocompatibility
- Calcium phosphate
- Mechanical properties
- Porous structure
ASJC Scopus subject areas
- Materials Science(all)
Cite this
Coextrusion-based 3D plotting of ceramic pastes for porous calcium phosphate scaffolds comprised of hollow filaments. / Jo, In Hwan; Koh, Young-Hag; Kim, Hyoun Ee.
In: Materials, Vol. 11, No. 6, 911, 29.05.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Coextrusion-based 3D plotting of ceramic pastes for porous calcium phosphate scaffolds comprised of hollow filaments
AU - Jo, In Hwan
AU - Koh, Young-Hag
AU - Kim, Hyoun Ee
PY - 2018/5/29
Y1 - 2018/5/29
N2 - This paper demonstrates the utility of coextrusion-based 3D plotting of ceramic pastes (CoEx-3DP) as a new type of additive manufacturing (AM) technique, which can produce porous calcium phosphate (CaP) ceramic scaffolds comprised of hollow CaP filaments. In this technique, green filaments with a controlled core/shell structure can be produced by coextruding an initial feedrod, comprised of the carbon black (CB) core and CaP shell, through a fine nozzle in an acetone bath and then deposited in a controlled manner according to predetermined paths. In addition, channels in CaP filaments can be created through the removal of the CB cores during heat-treatment. Produced CaP scaffolds had two different types of pores with well-defined geometries: three-dimensionally interconnected pores (~360 × 230 μm2 in sizes) and channels (> 100 μm in diameter) in hollow CaP filaments. The porous scaffolds showed high compressive strengths of ~12.3 ± 2.2 MPa at a high porosity of ~73 vol % when compressed parallel to the direction of the hollow CaP filaments. In addition, the mechanical properties of porous CaP scaffolds could be tailored by adjusting their porosity, for example, compressive strengths of 4.8 ± 1.1 MPa at a porosity of ~82 vol %. The porous CaP scaffold showed good biocompatibility, which was assessed by in vitro cell tests, where several the cells adhered to and spread actively with the outer and inner surfaces of the hollow CaP filaments.
AB - This paper demonstrates the utility of coextrusion-based 3D plotting of ceramic pastes (CoEx-3DP) as a new type of additive manufacturing (AM) technique, which can produce porous calcium phosphate (CaP) ceramic scaffolds comprised of hollow CaP filaments. In this technique, green filaments with a controlled core/shell structure can be produced by coextruding an initial feedrod, comprised of the carbon black (CB) core and CaP shell, through a fine nozzle in an acetone bath and then deposited in a controlled manner according to predetermined paths. In addition, channels in CaP filaments can be created through the removal of the CB cores during heat-treatment. Produced CaP scaffolds had two different types of pores with well-defined geometries: three-dimensionally interconnected pores (~360 × 230 μm2 in sizes) and channels (> 100 μm in diameter) in hollow CaP filaments. The porous scaffolds showed high compressive strengths of ~12.3 ± 2.2 MPa at a high porosity of ~73 vol % when compressed parallel to the direction of the hollow CaP filaments. In addition, the mechanical properties of porous CaP scaffolds could be tailored by adjusting their porosity, for example, compressive strengths of 4.8 ± 1.1 MPa at a porosity of ~82 vol %. The porous CaP scaffold showed good biocompatibility, which was assessed by in vitro cell tests, where several the cells adhered to and spread actively with the outer and inner surfaces of the hollow CaP filaments.
KW - Additive manufacturing
KW - Biocompatibility
KW - Calcium phosphate
KW - Mechanical properties
KW - Porous structure
UR - http://www.scopus.com/inward/record.url?scp=85047815448&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047815448&partnerID=8YFLogxK
U2 - 10.3390/ma11060911
DO - 10.3390/ma11060911
M3 - Article
AN - SCOPUS:85047815448
VL - 11
JO - Materials
JF - Materials
SN - 1996-1944
IS - 6
M1 - 911
ER -