Cognitive stimulation as a therapeutic modality for dementia: A meta-analysis

Kayoung Kim, Ji Won Han, Yoonseop So, Jiyeong Seo, You Joung Kim, Joon Hyuk Park, Seok Bum Lee, Jung Jae Lee, Hyun-Ghang Jeong, Tae Hui Kim, Ki Woong Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)


Objective Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials (RCTs) on the efficacy of CS in people with dementia. Methods Data sources were identified by searching PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library. A total of 7,354 articles were identified, and of these, 30 RCTs were selected based on the selection criteria. Of these 30 RCTs, 14 were finally included in our meta-analysis [731 participants with dementia; 412 received CS (CS group) and 319 received usual care (control group)]. Results We found that the people with dementia had a moderate benefit from CS. The mean difference between the CS and control groups was 2.21 [95% CI (0.93, 3.49), Z=3.38, p=0.00007] in the Alzheimer’s Disease Assessment Scale-Cognition and 1.41 [95% CI (0.98, 1.84), Z=6.39, p<0.00001] in the Mini-Mental State Examination. CS also improved quality of life in people with dementia [95% CI (0.72, 3.38), Z=3.02, p=0.003]. Conclusion CS is effective for improving cognition and quality of life in people with dementia; however, its effects were small to moderate.

Original languageEnglish
Pages (from-to)626-639
Number of pages14
JournalPsychiatry Investigation
Issue number5
Publication statusPublished - 2017 Sep 1


  • Cognition
  • Cognitive stimulation
  • Dementia
  • Meta-analysis
  • Quality of life

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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  • Cite this

    Kim, K., Han, J. W., So, Y., Seo, J., Kim, Y. J., Park, J. H., Lee, S. B., Lee, J. J., Jeong, H-G., Kim, T. H., & Kim, K. W. (2017). Cognitive stimulation as a therapeutic modality for dementia: A meta-analysis. Psychiatry Investigation, 14(5), 626-639.