Coixlachryside B: a new benzoxazinoid glycoside from the roots of Coix lachryma-jobi var. ma-yuen (Gramineae)

Yun Hyeok Choi, Chun Whan Choi, Seong Hyun Hong, Se Kyu Park, Joa Sub Oh, Dongho Lee, Seong Su Hong

Research output: Contribution to journalArticle

Abstract

Coix lachryma-jobi L. var. ma-yuen has been a source of food and traditional folk medicine in some parts of Asia for thousands of years; however, the roots of this plant have not been phytochemically investigated. Herein, we report the isolation of a new benzoxazinoid glycoside, coixlachryside B (1), along with ten known compounds (2–11), from the roots of C. lachryma-jobi var. ma-yuen using a variety of chromatographic methods. Among the known compounds, the absolute configuration of compound 4 was determined. The structures of all compounds were elucidated by interpreting NMR spectroscopic data, and experimental and calculated electronic circular dichroism spectra.

Original languageEnglish
JournalJournal of Asian Natural Products Research
DOIs
Publication statusAccepted/In press - 2018 Jan 1

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Keywords

  • benzoxazinoid
  • Coix lachryma-jobi var. ma-yuen
  • coixlachryside
  • Gramineae
  • phenolic compounds

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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