Combinatorial rosamine library and application to in vivo glutathione probe

Young Hoon Ahn, Jun Seok Lee, Young Tae Chang

Research output: Contribution to journalArticlepeer-review

203 Citations (Scopus)

Abstract

Combinatorial approach on fluorescent rosamine library was developed using solid-phase chemistry. A highly selective library member (H22) toward reduced glutathione (GSH) was discovered, demonstrating the capability of in vivo GSH level sensing in live cells.

Original languageEnglish
Pages (from-to)4510-4511
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number15
DOIs
Publication statusPublished - 2007 Apr 18
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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