Abstract
We report a novel fluorescent molecular conjugate, V-M1, enabling an accurate visualization of tumor tissues. The emission wavelength of V-M1 exceeds 650 nm, which is well within the near-infrared therapeutic window. Tumor accumulation of this cationic dye allows the visualization of cancerous cells as a function of mitochondrial viscosity.
| Original language | English |
|---|---|
| Pages (from-to) | 6684-6687 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 56 |
| Issue number | 49 |
| DOIs | |
| Publication status | Published - 2020 Jun 21 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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Yu, L., Yu, L., Zhang, J. F., Li, M., Jiang, D., Zhou, Y., Verwilst, P., & Kim, J. S. (2020). Combining viscosity-restricted intramolecular motion and mitochondrial targeting leads to selective tumor visualization. Chemical Communications, 56(49), 6684-6687. https://doi.org/10.1039/d0cc02943b