Common-path Fourier-domain optical coherence tomography in ophthalmology applications

Jae Ho Han, Xuan Liu, Kang Zhang, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

We have demonstrated in vivo three-dimensional imaging and estimated localized and quantitative hemoglobin oxygen saturation (SO 2) of blood vessel by using a simple, easy to operate common-path Fourier-domain optical coherence tomography (OCT) system. The common-path OCT system can be easily integrated with various surgical tools and we demonstrated its usefulness by imaging outer and inner intraocular tissues such as cornea and neurosensory retinal layers as well as detecting SO 2 level from a chicken embryo. The system uses 800nm near infrared broadband light sources and has axial resolution as low as 3μm in air. Self-adaptive scanning mechanism with real-time surface recognition and feedback control was also applied to the probe where the scanning probe tracks the sample surface variance and effective imaging depth was largely extended to the probe's free-moving range.

Original languageEnglish
Title of host publication2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Pages163-166
Number of pages4
DOIs
Publication statusPublished - 2009 Jul 23
Externally publishedYes
Event2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009 - Bethesda, MD, United States
Duration: 2009 Apr 92009 Apr 10

Other

Other2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
CountryUnited States
CityBethesda, MD
Period09/4/909/4/10

Fingerprint

Ophthalmology
Optical tomography
Imaging techniques
Hemoglobin oxygen saturation
Scanning
Blood vessels
Feedback control
Light sources
Tissue
Infrared radiation
Air

ASJC Scopus subject areas

  • Computational Theory and Mathematics
  • Biomedical Engineering
  • Electrical and Electronic Engineering

Cite this

Han, J. H., Liu, X., Zhang, K., & Kang, J. U. (2009). Common-path Fourier-domain optical coherence tomography in ophthalmology applications. In 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009 (pp. 163-166). [4906735] https://doi.org/10.1109/LISSA.2009.4906735

Common-path Fourier-domain optical coherence tomography in ophthalmology applications. / Han, Jae Ho; Liu, Xuan; Zhang, Kang; Kang, Jin U.

2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009. 2009. p. 163-166 4906735.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Han, JH, Liu, X, Zhang, K & Kang, JU 2009, Common-path Fourier-domain optical coherence tomography in ophthalmology applications. in 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009., 4906735, pp. 163-166, 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009, Bethesda, MD, United States, 09/4/9. https://doi.org/10.1109/LISSA.2009.4906735
Han JH, Liu X, Zhang K, Kang JU. Common-path Fourier-domain optical coherence tomography in ophthalmology applications. In 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009. 2009. p. 163-166. 4906735 https://doi.org/10.1109/LISSA.2009.4906735
Han, Jae Ho ; Liu, Xuan ; Zhang, Kang ; Kang, Jin U. / Common-path Fourier-domain optical coherence tomography in ophthalmology applications. 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009. 2009. pp. 163-166
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