Comparison between upper and lower limb lengthening in patients with achondroplasia

A retrospective study

S. J. Kim, M. V. Agashe, S. H. Song, H. J. Choi, H. Lee, Hae Ryong Song

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Lengthening of the humerus is now an established technique. We compared the complications of humeral lengthening with those of femoral lengthening and investigated whether or not the callus formation in the humerus proceeds at a higher rate than that in the femur. A total of 24 humeral and 24 femoral lengthenings were performed on 12 patients with achondroplasia. We measured the pixel value ratio (PVR) of the lengthened area on radiographs and each radiograph was analysed for the shape, type and density of the callus. The quality of life (QOL) of the patients after humeral lengthening was compared with that prior to surgery. The complication rate per segment of humerus and femur was 0.87% and 1.37%, respectively. In the humerus the PVR was significantly higher than that of the femur. Lower limbs were associated with an increased incidence of concave, lateral and central callus shapes. Humeral lengthening had a lower complication rate than lower-limb lengthening, and QOL increased significantly after humeral lengthening. Callus formation in the humerus during the distraction period proceeded at a significantly higher rate than that in the femur. These findings indicate that humeral lengthening has an important role in the management of patients with achondroplasia.

Original languageEnglish
Pages (from-to)128-133
Number of pages6
JournalJournal of Bone and Joint Surgery - Series B
Volume94 B
Issue number1
DOIs
Publication statusPublished - 2012 Jan 1

Fingerprint

Achondroplasia
Humerus
Bony Callus
Lower Extremity
Retrospective Studies
Femur
Thigh
Quality of Life
Incidence

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Comparison between upper and lower limb lengthening in patients with achondroplasia : A retrospective study. / Kim, S. J.; Agashe, M. V.; Song, S. H.; Choi, H. J.; Lee, H.; Song, Hae Ryong.

In: Journal of Bone and Joint Surgery - Series B, Vol. 94 B, No. 1, 01.01.2012, p. 128-133.

Research output: Contribution to journalArticle

Kim, S. J. ; Agashe, M. V. ; Song, S. H. ; Choi, H. J. ; Lee, H. ; Song, Hae Ryong. / Comparison between upper and lower limb lengthening in patients with achondroplasia : A retrospective study. In: Journal of Bone and Joint Surgery - Series B. 2012 ; Vol. 94 B, No. 1. pp. 128-133.
@article{20d746acde6b417cbcf8a025c73c7e97,
title = "Comparison between upper and lower limb lengthening in patients with achondroplasia: A retrospective study",
abstract = "Lengthening of the humerus is now an established technique. We compared the complications of humeral lengthening with those of femoral lengthening and investigated whether or not the callus formation in the humerus proceeds at a higher rate than that in the femur. A total of 24 humeral and 24 femoral lengthenings were performed on 12 patients with achondroplasia. We measured the pixel value ratio (PVR) of the lengthened area on radiographs and each radiograph was analysed for the shape, type and density of the callus. The quality of life (QOL) of the patients after humeral lengthening was compared with that prior to surgery. The complication rate per segment of humerus and femur was 0.87{\%} and 1.37{\%}, respectively. In the humerus the PVR was significantly higher than that of the femur. Lower limbs were associated with an increased incidence of concave, lateral and central callus shapes. Humeral lengthening had a lower complication rate than lower-limb lengthening, and QOL increased significantly after humeral lengthening. Callus formation in the humerus during the distraction period proceeded at a significantly higher rate than that in the femur. These findings indicate that humeral lengthening has an important role in the management of patients with achondroplasia.",
author = "Kim, {S. J.} and Agashe, {M. V.} and Song, {S. H.} and Choi, {H. J.} and H. Lee and Song, {Hae Ryong}",
year = "2012",
month = "1",
day = "1",
doi = "10.1302/0301-620X.94B1.27567",
language = "English",
volume = "94 B",
pages = "128--133",
journal = "Bone and Joint Journal",
issn = "2049-4394",
publisher = "British Editorial Society of Bone and Joint Surgery",
number = "1",

}

TY - JOUR

T1 - Comparison between upper and lower limb lengthening in patients with achondroplasia

T2 - A retrospective study

AU - Kim, S. J.

AU - Agashe, M. V.

AU - Song, S. H.

AU - Choi, H. J.

AU - Lee, H.

AU - Song, Hae Ryong

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Lengthening of the humerus is now an established technique. We compared the complications of humeral lengthening with those of femoral lengthening and investigated whether or not the callus formation in the humerus proceeds at a higher rate than that in the femur. A total of 24 humeral and 24 femoral lengthenings were performed on 12 patients with achondroplasia. We measured the pixel value ratio (PVR) of the lengthened area on radiographs and each radiograph was analysed for the shape, type and density of the callus. The quality of life (QOL) of the patients after humeral lengthening was compared with that prior to surgery. The complication rate per segment of humerus and femur was 0.87% and 1.37%, respectively. In the humerus the PVR was significantly higher than that of the femur. Lower limbs were associated with an increased incidence of concave, lateral and central callus shapes. Humeral lengthening had a lower complication rate than lower-limb lengthening, and QOL increased significantly after humeral lengthening. Callus formation in the humerus during the distraction period proceeded at a significantly higher rate than that in the femur. These findings indicate that humeral lengthening has an important role in the management of patients with achondroplasia.

AB - Lengthening of the humerus is now an established technique. We compared the complications of humeral lengthening with those of femoral lengthening and investigated whether or not the callus formation in the humerus proceeds at a higher rate than that in the femur. A total of 24 humeral and 24 femoral lengthenings were performed on 12 patients with achondroplasia. We measured the pixel value ratio (PVR) of the lengthened area on radiographs and each radiograph was analysed for the shape, type and density of the callus. The quality of life (QOL) of the patients after humeral lengthening was compared with that prior to surgery. The complication rate per segment of humerus and femur was 0.87% and 1.37%, respectively. In the humerus the PVR was significantly higher than that of the femur. Lower limbs were associated with an increased incidence of concave, lateral and central callus shapes. Humeral lengthening had a lower complication rate than lower-limb lengthening, and QOL increased significantly after humeral lengthening. Callus formation in the humerus during the distraction period proceeded at a significantly higher rate than that in the femur. These findings indicate that humeral lengthening has an important role in the management of patients with achondroplasia.

UR - http://www.scopus.com/inward/record.url?scp=84862969595&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862969595&partnerID=8YFLogxK

U2 - 10.1302/0301-620X.94B1.27567

DO - 10.1302/0301-620X.94B1.27567

M3 - Article

VL - 94 B

SP - 128

EP - 133

JO - Bone and Joint Journal

JF - Bone and Joint Journal

SN - 2049-4394

IS - 1

ER -