Comparison of ΔFVC (% decrease in FVC at the PC20) between cough-variant asthma and classic asthma

Young Yoo, Jinho Yu, Sun Hee Lee, Do Kyun Kim, Sun Hee Choi, Chang Keun Kim, Young Yull Koh

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The percentage decrease in forced vital capacity (FVC) at the methacholine PC20 (Δ FVC) has been proposed as a surrogate marker of maximal airway response. The aim of this study was to compare the Δ FVC between patients with cough-variant asthma (CVA) and those with classic asthma (CA). We performed a retrospective analysis of methacholine challenge test data from 47 children who were diagnosed as having CVA and from 75 children who had CA of mild severity. The mean (± SD) Δ FVC was significantly (p = 0.001) lower in the CVA group (14.7 ± 3.4%) compared with the CA group (17.1 ± 4.4%), whereas PC20 was not different between the two groups. Our results suggest that CVA is associated with a lower level of maximal airway response than CA.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalJournal of Asthma
Volume44
Issue number1
DOIs
Publication statusPublished - 2007 Jan

Keywords

  • Classic asthma
  • Cough-variant asthma
  • PC
  • ΔFVC

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

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