Comparison of a single shot T1-weighted in- and out-of-phase magnetization prepared gradient recalled echo with a standard two-dimensional gradient recalled echo: Preliminary findings

Vasco Herédia, Miguel Ramalho, Rafael O.P. De Campos, Chang-Hee Lee, Brian Dale, Georgeta D. Vaidean, Richard C. Semelka

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: To compare in-phase (IP) /out-of-phase (OP) single shot magnetization-prepared gradient-recalled-echo (MP-GRE) with a standard two-dimensional gradient-recalled-echo (2D-GRE), and to compare image quality of MP-GRE in cooperative and noncooperative subjects. Materials and Methods: Ninety-six consecutive subjects (52 males, 44 females; mean age, 53.2 ± 16.7 years), both cooperative (n = 73) and noncooperative (n = 23) subjects who had MRI examinations including precontrast T1-weighted IP/OP MP-GRE with or without IP/OP 2D-GRE were included in the study. The sequences were independently qualitatively evaluated by two radiologists. Quantitative analysis of liver fat index, signal-to-noise ratio (SNR) and liver-lesion contrast-to-noise ratio (CNR) was also performed. Data were subjected to statistical analysis. Results: The visual detection of the presence or absence of liver steatosis showed no differences between 2D-GRE and MP-GRE imaging (k = 1). Minor differences were observed on image quality between MP-GRE and 2D-GRE in cooperative subjects, and between MP-GRE sequences performed in cooperative and noncooperative subjects. Liver fat index results were strongly positively correlated (r =.98; 95% confidence interval [CI] 0.97 to 0.98; P <.0001). Intercept (.14; 95% CI.13 to.15; P <.0001) and slope (.83; 95% CI.79 to.86; P <.0001) were statistically significant. Conclusion: IP/OP MP-GRE and 2D-GRE comparably demonstrate the presence or absence of hepatic steatosis. Image quality of MP-GRE was also comparable to 2D-GRE, and was not substantially adversely affected if subjects were unable to cooperate with breathholding instructions.

Original languageEnglish
Pages (from-to)1482-1490
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Volume33
Issue number6
DOIs
Publication statusPublished - 2011 Jun 1
Externally publishedYes

Fingerprint

Liver
Fats
Signal-To-Noise Ratio
Fatty Liver
Noise
Confidence Intervals
Radiologists

Keywords

  • in-phase and out-of-phase imaging
  • liver MR
  • motion resistant MR

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Comparison of a single shot T1-weighted in- and out-of-phase magnetization prepared gradient recalled echo with a standard two-dimensional gradient recalled echo : Preliminary findings. / Herédia, Vasco; Ramalho, Miguel; De Campos, Rafael O.P.; Lee, Chang-Hee; Dale, Brian; Vaidean, Georgeta D.; Semelka, Richard C.

In: Journal of Magnetic Resonance Imaging, Vol. 33, No. 6, 01.06.2011, p. 1482-1490.

Research output: Contribution to journalArticle

Herédia, Vasco ; Ramalho, Miguel ; De Campos, Rafael O.P. ; Lee, Chang-Hee ; Dale, Brian ; Vaidean, Georgeta D. ; Semelka, Richard C. / Comparison of a single shot T1-weighted in- and out-of-phase magnetization prepared gradient recalled echo with a standard two-dimensional gradient recalled echo : Preliminary findings. In: Journal of Magnetic Resonance Imaging. 2011 ; Vol. 33, No. 6. pp. 1482-1490.
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T1 - Comparison of a single shot T1-weighted in- and out-of-phase magnetization prepared gradient recalled echo with a standard two-dimensional gradient recalled echo

T2 - Preliminary findings

AU - Herédia, Vasco

AU - Ramalho, Miguel

AU - De Campos, Rafael O.P.

AU - Lee, Chang-Hee

AU - Dale, Brian

AU - Vaidean, Georgeta D.

AU - Semelka, Richard C.

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