Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

Won Joo Kwon, Joo Yeon Ko, Young Suck Ro, Myung Hwa Kim, Byung Soo Kim, Hye One Kim, Jae Hui Nam, Ga Young Lee, Mi Youn Park, Sang Wook Son, Jun Mo Yang, Dong Hun Lee, Ai Young Lee, Jun Young Lee, Sung Eun Chang, Hae Young Choi, Eun Joo Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: A comparison between responses to allergens based on the TRUE Test®(TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians. Objectives: To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC. Materials & methods: Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC. Results: The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance. Conclusions: We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

Original languageEnglish
Pages (from-to)573-578
Number of pages6
JournalEuropean Journal of Dermatology
Volume27
Issue number6
DOIs
Publication statusPublished - 2017 Nov 1

Keywords

  • Concordance
  • IQ® Chamber
  • Korean standard series
  • Patch test
  • TRUE Test®

ASJC Scopus subject areas

  • Dermatology

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    Kwon, W. J., Ko, J. Y., Ro, Y. S., Kim, M. H., Kim, B. S., Kim, H. O., Nam, J. H., Lee, G. Y., Park, M. Y., Son, S. W., Yang, J. M., Lee, D. H., Lee, A. Y., Lee, J. Y., Chang, S. E., Choi, H. Y., & Park, E. J. (2017). Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients. European Journal of Dermatology, 27(6), 573-578. https://doi.org/10.1684/ejd.2017.3139