Abstract
Background: Meyer dysplasia (MD) is a rare disease but readily mistaken for Legg-Calvé-Perthes disease (LCPD). Although most published studies on MD have characterized and differentiated it from LCPD radiologically and clinically, differences with regard to bone age delay and recovery have not been sought. We deemed it necessary to distinguish bone age delay and recovery patterns between the two entities for better differentiation, prognostication, and parental advice. Methods: Bone age delay and recovery of eight patients who were initially diagnosed with LCPD but were found to have MD were retrospectively reviewed and compared with those of age-matched patients with LCPD. Based on hand radiographs, the radius-ulna-short bones (RUSs) and carpal bone ages were determined using the Tanner and Whitehouse 3 (TW3) method. Minimum follow-up was 2 years (range 2-5 years). Differences in RUS and carpal bone ages and recovery patterns between the two entities were analyzed using trend lines in scatter plots. Results: The mean delay of RUS bone age was significantly less in MD (0.52 ± 0.87 years) than in LCPD (1.11 ± 0.99 years). However, the difference between the mean carpal bone age delay in MD (1.13 ± 1.28 years) and LCPD (1.47 ± 1.19 years) was not significant. Trend lines showed faster bone age recovery patterns in MD than in LCPD. Conclusions: Bone age was delayed in both MD and LCPD but was less delayed in the former. RUS bone age showed more significant differences than carpal bone age when comparing the two entities and hence might be more useful for differentiating the two. Earlier bone age recovery patterns may be anticipated in patients with MD.
| Original language | English |
|---|---|
| Pages (from-to) | 746-752 |
| Number of pages | 7 |
| Journal | Journal of Orthopaedic Science |
| Volume | 15 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2010 Nov 1 |
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ASJC Scopus subject areas
- Orthopedics and Sports Medicine
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Comparison of bone age delay and recovery in Meyer dysplasia and Legg-Calvé-Perthes disease : A pilot study. / Sun, Xiao Tang; Easwar, T. R.; Cielo, Balce; Song, Sang Heon; Kim, Seung Ju; Song, Hae Ryong.
In: Journal of Orthopaedic Science, Vol. 15, No. 6, 01.11.2010, p. 746-752.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of bone age delay and recovery in Meyer dysplasia and Legg-Calvé-Perthes disease
T2 - A pilot study
AU - Sun, Xiao Tang
AU - Easwar, T. R.
AU - Cielo, Balce
AU - Song, Sang Heon
AU - Kim, Seung Ju
AU - Song, Hae Ryong
PY - 2010/11/1
Y1 - 2010/11/1
N2 - Background: Meyer dysplasia (MD) is a rare disease but readily mistaken for Legg-Calvé-Perthes disease (LCPD). Although most published studies on MD have characterized and differentiated it from LCPD radiologically and clinically, differences with regard to bone age delay and recovery have not been sought. We deemed it necessary to distinguish bone age delay and recovery patterns between the two entities for better differentiation, prognostication, and parental advice. Methods: Bone age delay and recovery of eight patients who were initially diagnosed with LCPD but were found to have MD were retrospectively reviewed and compared with those of age-matched patients with LCPD. Based on hand radiographs, the radius-ulna-short bones (RUSs) and carpal bone ages were determined using the Tanner and Whitehouse 3 (TW3) method. Minimum follow-up was 2 years (range 2-5 years). Differences in RUS and carpal bone ages and recovery patterns between the two entities were analyzed using trend lines in scatter plots. Results: The mean delay of RUS bone age was significantly less in MD (0.52 ± 0.87 years) than in LCPD (1.11 ± 0.99 years). However, the difference between the mean carpal bone age delay in MD (1.13 ± 1.28 years) and LCPD (1.47 ± 1.19 years) was not significant. Trend lines showed faster bone age recovery patterns in MD than in LCPD. Conclusions: Bone age was delayed in both MD and LCPD but was less delayed in the former. RUS bone age showed more significant differences than carpal bone age when comparing the two entities and hence might be more useful for differentiating the two. Earlier bone age recovery patterns may be anticipated in patients with MD.
AB - Background: Meyer dysplasia (MD) is a rare disease but readily mistaken for Legg-Calvé-Perthes disease (LCPD). Although most published studies on MD have characterized and differentiated it from LCPD radiologically and clinically, differences with regard to bone age delay and recovery have not been sought. We deemed it necessary to distinguish bone age delay and recovery patterns between the two entities for better differentiation, prognostication, and parental advice. Methods: Bone age delay and recovery of eight patients who were initially diagnosed with LCPD but were found to have MD were retrospectively reviewed and compared with those of age-matched patients with LCPD. Based on hand radiographs, the radius-ulna-short bones (RUSs) and carpal bone ages were determined using the Tanner and Whitehouse 3 (TW3) method. Minimum follow-up was 2 years (range 2-5 years). Differences in RUS and carpal bone ages and recovery patterns between the two entities were analyzed using trend lines in scatter plots. Results: The mean delay of RUS bone age was significantly less in MD (0.52 ± 0.87 years) than in LCPD (1.11 ± 0.99 years). However, the difference between the mean carpal bone age delay in MD (1.13 ± 1.28 years) and LCPD (1.47 ± 1.19 years) was not significant. Trend lines showed faster bone age recovery patterns in MD than in LCPD. Conclusions: Bone age was delayed in both MD and LCPD but was less delayed in the former. RUS bone age showed more significant differences than carpal bone age when comparing the two entities and hence might be more useful for differentiating the two. Earlier bone age recovery patterns may be anticipated in patients with MD.
UR - http://www.scopus.com/inward/record.url?scp=78651236259&partnerID=8YFLogxK
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U2 - 10.1007/s00776-010-1537-2
DO - 10.1007/s00776-010-1537-2
M3 - Article
C2 - 21116891
AN - SCOPUS:78651236259
VL - 15
SP - 746
EP - 752
JO - Journal of Orthopaedic Science
JF - Journal of Orthopaedic Science
SN - 0949-2658
IS - 6
ER -