Comparison of cornea endothelial cell counts after combined phacovitrectomy versus pars plana vitrectomy with fragmentation

Youngsub Eom, Seong-Woo Kim, Jaemoon Ahn, Jee Taek Kim, Kuhl Huh

Research output: Contribution to journalArticle

6 Citations (Scopus)


Background: To compare postoperative cornea endothelial cell loss between combined phacovitrectomy and pars plana vitrectomy (PPV) with fragmentation. Methods: Eighty-eight consecutive patients (92 eyes) who underwent combined phacovitrectomy (53 eyes from 50 patients) or PPV with fragmentation (39 eyes from 38 patients) were enrolled in this retrospective study. Endothelial cell density (ECD) was calculated with specular microscopy at 1 and 3 months after surgery. Results: At 3 months after surgery, the mean ECD decreased significantly from 2,646∈±∈296 cells/mm2 to 2,422∈±∈347 cells/mm2 in the combined phacovitrectomy group (P∈<∈0.001). However, the PPV with fragmentation group did not show any significant changes in ECD during the same period (from 2,123∈±∈628 cells/mm2 to 2,073∈±∈574 cells/mm2). The mean endothelial cell loss in the combined phacovitrectomy group (7.9 and 9.5 %) was significantly higher than that in the PPV with fragmentation group (0.7 and 2.4 %) both at 1 and 3 months postoperatively (P∈=∈0.001 and P∈=∈0.001 respectively). Conclusion: In this study, corneal endothelial cell loss during the early postoperative period was significantly higher after combined phacovitrectomy than after PPV with fragmentation.

Original languageEnglish
Pages (from-to)2187-2193
Number of pages7
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number9
Publication statusPublished - 2013 Aug 16



  • Combined phacovitrectomy
  • Cornea endothelial cell counts
  • Pars plana vitrectomy with fragmentation

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this