Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease

Michael S. Lee, Seung-Woon Rha, Seung-Kyu Han, Byoung Geol Choi, Se Yeon Choi, Jabar Ali, Shaopeng Xu, Harris Abdullah Ngow, Jae Joong Lee, Kwang No Lee, Ji Bak Kim, Sunki Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Jeremy KongDong Joo Oh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

OBJECTIVE: Peripheral arterial disease (PAD) is associated with poor outcomes. We assessed the clinical outcomes of diabetic versus non-diabetic patients with PAD who underwent peripheral transluminal angioplasty (PTA). Methods: The outcomes of 239 consecutive patients with symptomatic PAD who underwent PTA were analyzed. Restenosis and clinical outcomes were assessed at a follow-up of 2 years. Results: Diabetic patients had a higher percentage of wound as the initial diagnosis for PTA (72.7% vs 14.2%; P<.001), chronic kidney disease (26.7% vs 6.3%; P<.01), need for dialysis (19.3% vs 3.1%; P<.01), and coronary artery disease (67.6% vs 50.7%; P≤.02). Infrapopliteal PTA was more commonly performed in the diabetic group (70.4% vs 25.3%; P<.001). Diabetic patients had lower rates of angiographic follow-up at 8 months (38.6% vs 60.3%; P<.01). Diabetic patients had higher binary restenosis (54.4% vs 31.5%; P≤.02) and had a trend toward a higher incidence of total occlusion (34.0% vs 19.5%; P≤.08). At 2-year follow-up, the amputation rate was higher in the diabetic group (24.4% vs 1.5%; P<.001) despite PTA. CONCLUSION: Diabetic patients more frequently presented with critical limb ischemia compared with non-diabetic patients and had higher rates of restenosis and amputation at 2 years following standard PTA. Improved therapies are needed for this high-risk group of patients.

Original languageEnglish
Pages (from-to)167-171
Number of pages5
JournalJournal of Invasive Cardiology
Volume27
Issue number3
Publication statusPublished - 2015 Mar 1

Fingerprint

Peripheral Arterial Disease
Angioplasty
Amputation
Chronic Renal Insufficiency
Coronary Artery Disease
Dialysis
Ischemia
Extremities
Incidence
Wounds and Injuries

Keywords

  • Amputation
  • critical limb ischemia
  • peripheral transluminal angioplasty
  • PTA

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease. / Lee, Michael S.; Rha, Seung-Woon; Han, Seung-Kyu; Choi, Byoung Geol; Choi, Se Yeon; Ali, Jabar; Xu, Shaopeng; Ngow, Harris Abdullah; Lee, Jae Joong; Lee, Kwang No; Kim, Ji Bak; Lee, Sunki; Na, Jin Oh; Choi, Cheol Ung; Lim, Hong Euy; Kim, Jin Won; Kim, Eung Ju; Park, Chang Gyu; Seo, Hong Seog; Kong, Jeremy; Oh, Dong Joo.

In: Journal of Invasive Cardiology, Vol. 27, No. 3, 01.03.2015, p. 167-171.

Research output: Contribution to journalArticle

Lee, MS, Rha, S-W, Han, S-K, Choi, BG, Choi, SY, Ali, J, Xu, S, Ngow, HA, Lee, JJ, Lee, KN, Kim, JB, Lee, S, Na, JO, Choi, CU, Lim, HE, Kim, JW, Kim, EJ, Park, CG, Seo, HS, Kong, J & Oh, DJ 2015, 'Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease', Journal of Invasive Cardiology, vol. 27, no. 3, pp. 167-171.
Lee, Michael S. ; Rha, Seung-Woon ; Han, Seung-Kyu ; Choi, Byoung Geol ; Choi, Se Yeon ; Ali, Jabar ; Xu, Shaopeng ; Ngow, Harris Abdullah ; Lee, Jae Joong ; Lee, Kwang No ; Kim, Ji Bak ; Lee, Sunki ; Na, Jin Oh ; Choi, Cheol Ung ; Lim, Hong Euy ; Kim, Jin Won ; Kim, Eung Ju ; Park, Chang Gyu ; Seo, Hong Seog ; Kong, Jeremy ; Oh, Dong Joo. / Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease. In: Journal of Invasive Cardiology. 2015 ; Vol. 27, No. 3. pp. 167-171.
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AU - Rha, Seung-Woon

AU - Han, Seung-Kyu

AU - Choi, Byoung Geol

AU - Choi, Se Yeon

AU - Ali, Jabar

AU - Xu, Shaopeng

AU - Ngow, Harris Abdullah

AU - Lee, Jae Joong

AU - Lee, Kwang No

AU - Kim, Ji Bak

AU - Lee, Sunki

AU - Na, Jin Oh

AU - Choi, Cheol Ung

AU - Lim, Hong Euy

AU - Kim, Jin Won

AU - Kim, Eung Ju

AU - Park, Chang Gyu

AU - Seo, Hong Seog

AU - Kong, Jeremy

AU - Oh, Dong Joo

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N2 - OBJECTIVE: Peripheral arterial disease (PAD) is associated with poor outcomes. We assessed the clinical outcomes of diabetic versus non-diabetic patients with PAD who underwent peripheral transluminal angioplasty (PTA). Methods: The outcomes of 239 consecutive patients with symptomatic PAD who underwent PTA were analyzed. Restenosis and clinical outcomes were assessed at a follow-up of 2 years. Results: Diabetic patients had a higher percentage of wound as the initial diagnosis for PTA (72.7% vs 14.2%; P<.001), chronic kidney disease (26.7% vs 6.3%; P<.01), need for dialysis (19.3% vs 3.1%; P<.01), and coronary artery disease (67.6% vs 50.7%; P≤.02). Infrapopliteal PTA was more commonly performed in the diabetic group (70.4% vs 25.3%; P<.001). Diabetic patients had lower rates of angiographic follow-up at 8 months (38.6% vs 60.3%; P<.01). Diabetic patients had higher binary restenosis (54.4% vs 31.5%; P≤.02) and had a trend toward a higher incidence of total occlusion (34.0% vs 19.5%; P≤.08). At 2-year follow-up, the amputation rate was higher in the diabetic group (24.4% vs 1.5%; P<.001) despite PTA. CONCLUSION: Diabetic patients more frequently presented with critical limb ischemia compared with non-diabetic patients and had higher rates of restenosis and amputation at 2 years following standard PTA. Improved therapies are needed for this high-risk group of patients.

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KW - Amputation

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