Comparison of filtered back projection, hybrid iterative reconstruction, model-based iterative reconstruction, and virtual monoenergetic reconstruction images at both low-and standard-dose settings in measurement of emphysema volume and airway wall thickness: A CT phantom study

Cherry Kim, Ki Yeol Lee, Chol Shin, Eun-Young Kang, Yu Whan Oh, Moin Ha, Chang Sub Ko, Jaehyung Cha

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To evaluate the accuracy of emphysema volume (EV) and airway measurements (AMs) produced by various iterative reconstruction (IR) algorithms and virtual monoenergetic images (VME) at both low-and standard-dose settings. Materials and Methods: Computed tomography (CT) images were obtained on phantom at both low-(30 mAs at 120 kVp) and standard-doses (100 mAs at 120 kVp). Each CT scan was reconstructed using filtered back projection, hybrid IR (iDose4; Philips Healthcare), model-based IR (IMR-R1, IMR-ST1, IMR-SP1; Philips Healthcare), and VME at 70 keV (VME70). The EV of each air column and wall area percentage (WA%) of each airway tube were measured in all algorithms. Absolute percentage measurement errors of EV (APEvol) and AM (APEWA%) were then calculated. Results: Emphysema volume was most accurately measured in IMR-R1 (APEvol in low-dose, 0.053 ± 0.002; APEvol in standard-dose, 0.047 ± 0.003; all p < 0.001) and AM was the most accurate in IMR-SP1 on both low-and standard-doses CT (APEWA% in low-dose, 0.067 ± 0.002; APEWA% in standard-dose, 0.06 ± 0.003; all p < 0.001). There were no significant differences in the APEvol of IMR-R1 between low-and standard-doses (all p > 0.05). VME70 showed a significantly higher APEvol than iDose4, IMR-R1, and IMR-ST1 (all p < 0.004). VME70 also showed a significantly higher APEWA% compared with the other algorithms (all p < 0.001). Conclusion: IMR was the most accurate technique for measurement of both EV and airway wall thickness. However, VME70 did not show a significantly better accuracy compared with other algorithms.

Original languageEnglish
Pages (from-to)809-817
Number of pages9
JournalKorean Journal of Radiology
Volume19
Issue number4
DOIs
Publication statusPublished - 2018 Jul 1

Keywords

  • Airway wall thickness
  • Computed tomography
  • Emphysema volume
  • Model-based iterative reconstruction
  • Virtual monoenergetic image

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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