Comparison of in vivo antibacterial and antithrombotic activities of two types of pulmonary artery catheters in pig

Jung Wook Han, Yeon Soo Shin, Jung Ju Kim, Ho Sung Son

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: During pulmonary artery catheter (PAC) implantation, inaccurate measurements of hemodynamic parameters due to infection or thrombosis of PAC can result in severe complications. Method: In order to develop a new PAC material, we evaluated the antibacterial and antithrombotic activities of the two types of PAC (Swan Ganz catheter and prototype catheter) in 14 pigs. Results: In the 3-day group, bacterial infection rate was not different between the two types of PAC. In the 7-day group, bacterial infection rate of the prototype catheter was twice as elevated as that of the Swan-Ganz catheter. In the 3-day group, thrombus formation rate of the prototype catheter was twice as elevated as that of the Swan-Ganz catheter. In the 7-day group, thrombus formation rate was the same for the two types of PAC. Conclusion: Here, we report an experimental pig model that confirms differences in antibacterial and antithrombotic activities.

Original languageEnglish
Article number23
JournalBiomaterials Research
Volume21
Issue number1
DOIs
Publication statusPublished - 2017 Nov 15

Keywords

  • Infection
  • Pig
  • Pulmonary artery catheter
  • Thrombosis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Ceramics and Composites
  • Medicine (miscellaneous)

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