Comparison of predicted total lung capacity and total lung capacity by computed tomography in lung transplantation candidates

Sung Ho Hwang, Jin Gu Lee, Tae Hoon Kim, Hyo Chae Paik, Chul Hwan Park, Seokjin Haam

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: Lung size mismatch is a major cause of poor lung function and worse survival after lung transplantation (LTx). We compared predicted total lung capacity (pTLC) and TLC measured by chest computed tomography (TLCCT) in LTx candidates. Materials and Methods: We reviewed the medical records of patients on waiting lists for LTx. According to the results of pulmonary function tests, patients were divided into an obstructive disease group and restrictive disease group. The differences between pTLC calculated using the equation of the European Respiratory Society and TLCCT were analyzed in each group. Results: Ninety two patients met the criteria. Thirty five patients were included in the obstructive disease group, and 57 patients were included in the restrictive disease group. pTLC in the obstructive disease group (5.50±1.07 L) and restrictive disease group (5.57±1.03 L) had no statistical significance (p=0.747), while TLCCT in the restrictive disease group (3.17±1.15 L) was smaller than that I the obstructive disease group (4.21±1.38 L) (p<0.0001). TLCCT/pTLC was 0.770 in the obstructive disease group and 0.571 in the restrictive disease group. Conclusion: Regardless of pulmonary disease pattern, TLCCT was smaller than pTLC, and it was more apparent in restrictive lung disease. Therefore, we should consider the difference between TLCCT and pTLC, as well as lung disease patterns of candidates, in lung size matching for LTx.

Original languageEnglish
Pages (from-to)963-967
Number of pages5
JournalYonsei medical journal
Volume57
Issue number4
DOIs
Publication statusPublished - 2016 Jul 1

Fingerprint

Total Lung Capacity
Lung Transplantation
Tomography
Thorax
Lung Diseases
Lung
Waiting Lists
Respiratory Function Tests
Medical Records

Keywords

  • Donor selection
  • Lung transplantation
  • Pulmonary function test

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Comparison of predicted total lung capacity and total lung capacity by computed tomography in lung transplantation candidates. / Hwang, Sung Ho; Lee, Jin Gu; Kim, Tae Hoon; Paik, Hyo Chae; Park, Chul Hwan; Haam, Seokjin.

In: Yonsei medical journal, Vol. 57, No. 4, 01.07.2016, p. 963-967.

Research output: Contribution to journalArticle

Hwang, Sung Ho ; Lee, Jin Gu ; Kim, Tae Hoon ; Paik, Hyo Chae ; Park, Chul Hwan ; Haam, Seokjin. / Comparison of predicted total lung capacity and total lung capacity by computed tomography in lung transplantation candidates. In: Yonsei medical journal. 2016 ; Vol. 57, No. 4. pp. 963-967.
@article{31ba125d6e3041489d1823e6bbaaf069,
title = "Comparison of predicted total lung capacity and total lung capacity by computed tomography in lung transplantation candidates",
abstract = "Purpose: Lung size mismatch is a major cause of poor lung function and worse survival after lung transplantation (LTx). We compared predicted total lung capacity (pTLC) and TLC measured by chest computed tomography (TLCCT) in LTx candidates. Materials and Methods: We reviewed the medical records of patients on waiting lists for LTx. According to the results of pulmonary function tests, patients were divided into an obstructive disease group and restrictive disease group. The differences between pTLC calculated using the equation of the European Respiratory Society and TLCCT were analyzed in each group. Results: Ninety two patients met the criteria. Thirty five patients were included in the obstructive disease group, and 57 patients were included in the restrictive disease group. pTLC in the obstructive disease group (5.50±1.07 L) and restrictive disease group (5.57±1.03 L) had no statistical significance (p=0.747), while TLCCT in the restrictive disease group (3.17±1.15 L) was smaller than that I the obstructive disease group (4.21±1.38 L) (p<0.0001). TLCCT/pTLC was 0.770 in the obstructive disease group and 0.571 in the restrictive disease group. Conclusion: Regardless of pulmonary disease pattern, TLCCT was smaller than pTLC, and it was more apparent in restrictive lung disease. Therefore, we should consider the difference between TLCCT and pTLC, as well as lung disease patterns of candidates, in lung size matching for LTx.",
keywords = "Donor selection, Lung transplantation, Pulmonary function test",
author = "Hwang, {Sung Ho} and Lee, {Jin Gu} and Kim, {Tae Hoon} and Paik, {Hyo Chae} and Park, {Chul Hwan} and Seokjin Haam",
year = "2016",
month = "7",
day = "1",
doi = "10.3349/ymj.2016.57.4.963",
language = "English",
volume = "57",
pages = "963--967",
journal = "Yonsei Medical Journal",
issn = "0513-5796",
publisher = "Yonsei University College of Medicine",
number = "4",

}

TY - JOUR

T1 - Comparison of predicted total lung capacity and total lung capacity by computed tomography in lung transplantation candidates

AU - Hwang, Sung Ho

AU - Lee, Jin Gu

AU - Kim, Tae Hoon

AU - Paik, Hyo Chae

AU - Park, Chul Hwan

AU - Haam, Seokjin

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Purpose: Lung size mismatch is a major cause of poor lung function and worse survival after lung transplantation (LTx). We compared predicted total lung capacity (pTLC) and TLC measured by chest computed tomography (TLCCT) in LTx candidates. Materials and Methods: We reviewed the medical records of patients on waiting lists for LTx. According to the results of pulmonary function tests, patients were divided into an obstructive disease group and restrictive disease group. The differences between pTLC calculated using the equation of the European Respiratory Society and TLCCT were analyzed in each group. Results: Ninety two patients met the criteria. Thirty five patients were included in the obstructive disease group, and 57 patients were included in the restrictive disease group. pTLC in the obstructive disease group (5.50±1.07 L) and restrictive disease group (5.57±1.03 L) had no statistical significance (p=0.747), while TLCCT in the restrictive disease group (3.17±1.15 L) was smaller than that I the obstructive disease group (4.21±1.38 L) (p<0.0001). TLCCT/pTLC was 0.770 in the obstructive disease group and 0.571 in the restrictive disease group. Conclusion: Regardless of pulmonary disease pattern, TLCCT was smaller than pTLC, and it was more apparent in restrictive lung disease. Therefore, we should consider the difference between TLCCT and pTLC, as well as lung disease patterns of candidates, in lung size matching for LTx.

AB - Purpose: Lung size mismatch is a major cause of poor lung function and worse survival after lung transplantation (LTx). We compared predicted total lung capacity (pTLC) and TLC measured by chest computed tomography (TLCCT) in LTx candidates. Materials and Methods: We reviewed the medical records of patients on waiting lists for LTx. According to the results of pulmonary function tests, patients were divided into an obstructive disease group and restrictive disease group. The differences between pTLC calculated using the equation of the European Respiratory Society and TLCCT were analyzed in each group. Results: Ninety two patients met the criteria. Thirty five patients were included in the obstructive disease group, and 57 patients were included in the restrictive disease group. pTLC in the obstructive disease group (5.50±1.07 L) and restrictive disease group (5.57±1.03 L) had no statistical significance (p=0.747), while TLCCT in the restrictive disease group (3.17±1.15 L) was smaller than that I the obstructive disease group (4.21±1.38 L) (p<0.0001). TLCCT/pTLC was 0.770 in the obstructive disease group and 0.571 in the restrictive disease group. Conclusion: Regardless of pulmonary disease pattern, TLCCT was smaller than pTLC, and it was more apparent in restrictive lung disease. Therefore, we should consider the difference between TLCCT and pTLC, as well as lung disease patterns of candidates, in lung size matching for LTx.

KW - Donor selection

KW - Lung transplantation

KW - Pulmonary function test

UR - http://www.scopus.com/inward/record.url?scp=84969223232&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84969223232&partnerID=8YFLogxK

U2 - 10.3349/ymj.2016.57.4.963

DO - 10.3349/ymj.2016.57.4.963

M3 - Article

VL - 57

SP - 963

EP - 967

JO - Yonsei Medical Journal

JF - Yonsei Medical Journal

SN - 0513-5796

IS - 4

ER -