Comparison of serum levels and the placental expression of resistin between patients with preeclampsia and normal pregnant women

Hyun Joo Seol, Min Jeong Oh, Min Koo Yeo, Aeree Kim, Eung Seok Lee, Hai Joong Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective. The aim of this study was to evaluate serum resistin levels in women with preeclampsia compared to those in normal pregnant women and normal non-pregnant women, and to examine placental resistin expression. Methods. Serum resistin levels were measured by enzyme-linked immunosorbent assay and placental resistin expression was determined by immunohistochemistry. Results. Serum resistin levels were significantly elevated in women with preeclampsia compared to normal pregnant women and non-pregnant women. There was no significant difference in placental resistin expression. Conclusion. The placenta may not be the origin of the resistin that contributes to increased serum levels in women with preeclampsia.

Original languageEnglish
Pages (from-to)310-317
Number of pages8
JournalHypertension in Pregnancy
Volume29
Issue number3
DOIs
Publication statusPublished - 2010 Aug

Keywords

  • ELISA
  • Immunohistochemistry
  • Placenta
  • Preeclampsia
  • Resistin

ASJC Scopus subject areas

  • Internal Medicine
  • Obstetrics and Gynaecology

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