Abstract
Background: Optimal stenting strategy for long femoropopliteal artery lesions still remains undefined. Longer stent length has been shown to be associated with increased risk of restenosis. We sought to compare the efficacy of spot versus long stenting in the treatment of femoropopliteal artery disease. Methods: This study was designed as a multicenter randomized controlled trial to compare immediate and mid-term outcomes of spot versus long primary stenting for femoropopliteal arterial lesions. A total of 125 patients were randomized 1:1 to spot stenting group (n = 59) or long stenting group (n = 66). Results: All lesions were treated with self-expanding bare nitinol stents. Baseline clinical and lesion characteristics were similar between the 2 groups except for male gender and current smoker. The mean lesion length was 24.1 ± 8.8 cm. Technical success was achieved in all patients. The 1-year primary patency and TLR-free (target lesion revascularization) survival did not differ significantly between the 2 groups. However, the spot stenting group showed a trend toward higher primary patency (86.1% vs. 72.7%, P = 0.158) and TLR-free survival (94.2% vs. 82.5%, P = 0.120). The total stented length (hazard ratio [HR] 1.01, 95% confidence interval [CI] 1.00–1.01, P = 0.011) and age (HR 0.94, 95% CI 0.90–1.00, P = 0.035) were independent predictors of restenosis. Conclusions: The spot stenting appears to be more favorable than the long stenting in terms of primary patency and TLR-free survival, although the difference was not statistically significant. The stented length was an independent predictor of restenosis.
| Original language | English |
|---|---|
| Journal | Annals of Vascular Surgery |
| DOIs | |
| Publication status | Published - 2019 Jan 1 |
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ASJC Scopus subject areas
- Surgery
- Cardiology and Cardiovascular Medicine
Cite this
Comparison of Spot versus Long Stenting for Femoropopliteal Artery Disease. / PARADE Investigators.
In: Annals of Vascular Surgery, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of Spot versus Long Stenting for Femoropopliteal Artery Disease
AU - PARADE Investigators
AU - Ko, Young Guk
AU - Ahn, Chul Min
AU - Rha, Seung-Woon
AU - Yu, Cheol Woong
AU - Park, Sang Ho
AU - Lee, Seung Jin
AU - Lee, Jae Hwan
AU - Her, Sung Ho
AU - Kang, Woong Chol
AU - Cho, Young Seok
AU - Seo, Jae Bin
AU - Cho, Yun Hyeong
AU - Choi, Donghoon
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Background: Optimal stenting strategy for long femoropopliteal artery lesions still remains undefined. Longer stent length has been shown to be associated with increased risk of restenosis. We sought to compare the efficacy of spot versus long stenting in the treatment of femoropopliteal artery disease. Methods: This study was designed as a multicenter randomized controlled trial to compare immediate and mid-term outcomes of spot versus long primary stenting for femoropopliteal arterial lesions. A total of 125 patients were randomized 1:1 to spot stenting group (n = 59) or long stenting group (n = 66). Results: All lesions were treated with self-expanding bare nitinol stents. Baseline clinical and lesion characteristics were similar between the 2 groups except for male gender and current smoker. The mean lesion length was 24.1 ± 8.8 cm. Technical success was achieved in all patients. The 1-year primary patency and TLR-free (target lesion revascularization) survival did not differ significantly between the 2 groups. However, the spot stenting group showed a trend toward higher primary patency (86.1% vs. 72.7%, P = 0.158) and TLR-free survival (94.2% vs. 82.5%, P = 0.120). The total stented length (hazard ratio [HR] 1.01, 95% confidence interval [CI] 1.00–1.01, P = 0.011) and age (HR 0.94, 95% CI 0.90–1.00, P = 0.035) were independent predictors of restenosis. Conclusions: The spot stenting appears to be more favorable than the long stenting in terms of primary patency and TLR-free survival, although the difference was not statistically significant. The stented length was an independent predictor of restenosis.
AB - Background: Optimal stenting strategy for long femoropopliteal artery lesions still remains undefined. Longer stent length has been shown to be associated with increased risk of restenosis. We sought to compare the efficacy of spot versus long stenting in the treatment of femoropopliteal artery disease. Methods: This study was designed as a multicenter randomized controlled trial to compare immediate and mid-term outcomes of spot versus long primary stenting for femoropopliteal arterial lesions. A total of 125 patients were randomized 1:1 to spot stenting group (n = 59) or long stenting group (n = 66). Results: All lesions were treated with self-expanding bare nitinol stents. Baseline clinical and lesion characteristics were similar between the 2 groups except for male gender and current smoker. The mean lesion length was 24.1 ± 8.8 cm. Technical success was achieved in all patients. The 1-year primary patency and TLR-free (target lesion revascularization) survival did not differ significantly between the 2 groups. However, the spot stenting group showed a trend toward higher primary patency (86.1% vs. 72.7%, P = 0.158) and TLR-free survival (94.2% vs. 82.5%, P = 0.120). The total stented length (hazard ratio [HR] 1.01, 95% confidence interval [CI] 1.00–1.01, P = 0.011) and age (HR 0.94, 95% CI 0.90–1.00, P = 0.035) were independent predictors of restenosis. Conclusions: The spot stenting appears to be more favorable than the long stenting in terms of primary patency and TLR-free survival, although the difference was not statistically significant. The stented length was an independent predictor of restenosis.
UR - http://www.scopus.com/inward/record.url?scp=85062694981&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062694981&partnerID=8YFLogxK
U2 - 10.1016/j.avsg.2018.11.023
DO - 10.1016/j.avsg.2018.11.023
M3 - Article
C2 - 30769056
AN - SCOPUS:85062694981
JO - Annals of Vascular Surgery
JF - Annals of Vascular Surgery
SN - 0890-5096
ER -