Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis

Sang Rok Lee, Myung Ho Jeong, Sang Yeob Lim, Seo Na Hong, Kye Hun Kim, Il Suk Sohn, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Weon Kim, Young Keun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background and Objectives: Treating coronary in-stent restenosis (ISR) has become one of the major challenges for interventional cardiologists. The aim of this study was to compare the clinical effect of performing cutting balloon angioplasty (CBA) with implanting drug eluting stent (DES) for treating the focal type of instent restenosis (ISR). Subjects and Methods: We retrospectively analyzed 56 patients who were treated by CBA (Group I: 59.6±9.6 years, male: female=46: 10) and 20 patients who were treated by DES (Group II: 61.0±8.5 year, male: female=15: 5) between January 2002 and December 2004. All the patients had the focal type of ISR (Group I - type IB: IC: ID=23: 9: 26, Group II - type IB: IC: ID=10: 3: 7). The 6-month angiographically determined late loss and the major adverse cardiac events (MACE) were compared between the two groups. Results: The baseline clinical characteristics were similar between the two groups except for the high proportion of old myocardial infarction [4 (7.1%) and 3 (15%); respectively, p=0.02] and low left ventricular ejection fraction (62.6±8.8% vs. 55.2±13.8%, respectively, p=0.02) in group II. The acute gain after the procedure was higher in group II (1.86±0.53 mm vs. 2.54±0.20 mm, respectively, p<0.01). Follow-up angiography at 6 months was achieved in 40 of 56 (71.4%) patients in group I and in 15 of 20 patients (75%) in group II. The late loss was lower in group II than in group I (0.49±0.35 mm vs. 0.14±0.24 mm respectively, p<0.01). MACE during the 6-month follow-up developed in 8 patients (14.3%) of group I and in 1 patient (5.0%) of group II (p=0.04). Conclusion: DES is associated with a better clinical outcome than CBA for the treatment of the focal type of ISR.

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalKorean Circulation Journal
Volume36
Issue number4
Publication statusPublished - 2006 Apr 1
Externally publishedYes

Fingerprint

Drug-Eluting Stents
Balloon Angioplasty
Stents
Stroke Volume
Angiography
Myocardial Infarction

Keywords

  • Coronary disease
  • Stenosis
  • Stents

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis. / Lee, Sang Rok; Jeong, Myung Ho; Lim, Sang Yeob; Hong, Seo Na; Kim, Kye Hun; Sohn, Il Suk; Hong, Young Joon; Park, Hyung Wook; Kim, Ju Han; Kim, Weon; Ahn, Young Keun; Cho, Jeong Gwan; Park, Jong Chun; Kang, Jung Chaee.

In: Korean Circulation Journal, Vol. 36, No. 4, 01.04.2006, p. 279-284.

Research output: Contribution to journalArticle

Lee, SR, Jeong, MH, Lim, SY, Hong, SN, Kim, KH, Sohn, IS, Hong, YJ, Park, HW, Kim, JH, Kim, W, Ahn, YK, Cho, JG, Park, JC & Kang, JC 2006, 'Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis', Korean Circulation Journal, vol. 36, no. 4, pp. 279-284.
Lee, Sang Rok ; Jeong, Myung Ho ; Lim, Sang Yeob ; Hong, Seo Na ; Kim, Kye Hun ; Sohn, Il Suk ; Hong, Young Joon ; Park, Hyung Wook ; Kim, Ju Han ; Kim, Weon ; Ahn, Young Keun ; Cho, Jeong Gwan ; Park, Jong Chun ; Kang, Jung Chaee. / Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis. In: Korean Circulation Journal. 2006 ; Vol. 36, No. 4. pp. 279-284.
@article{e49cfa5e68424bd8938a246b8ec0d35b,
title = "Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis",
abstract = "Background and Objectives: Treating coronary in-stent restenosis (ISR) has become one of the major challenges for interventional cardiologists. The aim of this study was to compare the clinical effect of performing cutting balloon angioplasty (CBA) with implanting drug eluting stent (DES) for treating the focal type of instent restenosis (ISR). Subjects and Methods: We retrospectively analyzed 56 patients who were treated by CBA (Group I: 59.6±9.6 years, male: female=46: 10) and 20 patients who were treated by DES (Group II: 61.0±8.5 year, male: female=15: 5) between January 2002 and December 2004. All the patients had the focal type of ISR (Group I - type IB: IC: ID=23: 9: 26, Group II - type IB: IC: ID=10: 3: 7). The 6-month angiographically determined late loss and the major adverse cardiac events (MACE) were compared between the two groups. Results: The baseline clinical characteristics were similar between the two groups except for the high proportion of old myocardial infarction [4 (7.1{\%}) and 3 (15{\%}); respectively, p=0.02] and low left ventricular ejection fraction (62.6±8.8{\%} vs. 55.2±13.8{\%}, respectively, p=0.02) in group II. The acute gain after the procedure was higher in group II (1.86±0.53 mm vs. 2.54±0.20 mm, respectively, p<0.01). Follow-up angiography at 6 months was achieved in 40 of 56 (71.4{\%}) patients in group I and in 15 of 20 patients (75{\%}) in group II. The late loss was lower in group II than in group I (0.49±0.35 mm vs. 0.14±0.24 mm respectively, p<0.01). MACE during the 6-month follow-up developed in 8 patients (14.3{\%}) of group I and in 1 patient (5.0{\%}) of group II (p=0.04). Conclusion: DES is associated with a better clinical outcome than CBA for the treatment of the focal type of ISR.",
keywords = "Coronary disease, Stenosis, Stents",
author = "Lee, {Sang Rok} and Jeong, {Myung Ho} and Lim, {Sang Yeob} and Hong, {Seo Na} and Kim, {Kye Hun} and Sohn, {Il Suk} and Hong, {Young Joon} and Park, {Hyung Wook} and Kim, {Ju Han} and Weon Kim and Ahn, {Young Keun} and Cho, {Jeong Gwan} and Park, {Jong Chun} and Kang, {Jung Chaee}",
year = "2006",
month = "4",
day = "1",
language = "English",
volume = "36",
pages = "279--284",
journal = "Korean Circulation Journal",
issn = "1738-5520",
publisher = "Korean Society of Circulation",
number = "4",

}

TY - JOUR

T1 - Comparison of the clinical effect of cutting balloon angioplasty and drug-eluting stent for treating the focal type of in-stent restenosis

AU - Lee, Sang Rok

AU - Jeong, Myung Ho

AU - Lim, Sang Yeob

AU - Hong, Seo Na

AU - Kim, Kye Hun

AU - Sohn, Il Suk

AU - Hong, Young Joon

AU - Park, Hyung Wook

AU - Kim, Ju Han

AU - Kim, Weon

AU - Ahn, Young Keun

AU - Cho, Jeong Gwan

AU - Park, Jong Chun

AU - Kang, Jung Chaee

PY - 2006/4/1

Y1 - 2006/4/1

N2 - Background and Objectives: Treating coronary in-stent restenosis (ISR) has become one of the major challenges for interventional cardiologists. The aim of this study was to compare the clinical effect of performing cutting balloon angioplasty (CBA) with implanting drug eluting stent (DES) for treating the focal type of instent restenosis (ISR). Subjects and Methods: We retrospectively analyzed 56 patients who were treated by CBA (Group I: 59.6±9.6 years, male: female=46: 10) and 20 patients who were treated by DES (Group II: 61.0±8.5 year, male: female=15: 5) between January 2002 and December 2004. All the patients had the focal type of ISR (Group I - type IB: IC: ID=23: 9: 26, Group II - type IB: IC: ID=10: 3: 7). The 6-month angiographically determined late loss and the major adverse cardiac events (MACE) were compared between the two groups. Results: The baseline clinical characteristics were similar between the two groups except for the high proportion of old myocardial infarction [4 (7.1%) and 3 (15%); respectively, p=0.02] and low left ventricular ejection fraction (62.6±8.8% vs. 55.2±13.8%, respectively, p=0.02) in group II. The acute gain after the procedure was higher in group II (1.86±0.53 mm vs. 2.54±0.20 mm, respectively, p<0.01). Follow-up angiography at 6 months was achieved in 40 of 56 (71.4%) patients in group I and in 15 of 20 patients (75%) in group II. The late loss was lower in group II than in group I (0.49±0.35 mm vs. 0.14±0.24 mm respectively, p<0.01). MACE during the 6-month follow-up developed in 8 patients (14.3%) of group I and in 1 patient (5.0%) of group II (p=0.04). Conclusion: DES is associated with a better clinical outcome than CBA for the treatment of the focal type of ISR.

AB - Background and Objectives: Treating coronary in-stent restenosis (ISR) has become one of the major challenges for interventional cardiologists. The aim of this study was to compare the clinical effect of performing cutting balloon angioplasty (CBA) with implanting drug eluting stent (DES) for treating the focal type of instent restenosis (ISR). Subjects and Methods: We retrospectively analyzed 56 patients who were treated by CBA (Group I: 59.6±9.6 years, male: female=46: 10) and 20 patients who were treated by DES (Group II: 61.0±8.5 year, male: female=15: 5) between January 2002 and December 2004. All the patients had the focal type of ISR (Group I - type IB: IC: ID=23: 9: 26, Group II - type IB: IC: ID=10: 3: 7). The 6-month angiographically determined late loss and the major adverse cardiac events (MACE) were compared between the two groups. Results: The baseline clinical characteristics were similar between the two groups except for the high proportion of old myocardial infarction [4 (7.1%) and 3 (15%); respectively, p=0.02] and low left ventricular ejection fraction (62.6±8.8% vs. 55.2±13.8%, respectively, p=0.02) in group II. The acute gain after the procedure was higher in group II (1.86±0.53 mm vs. 2.54±0.20 mm, respectively, p<0.01). Follow-up angiography at 6 months was achieved in 40 of 56 (71.4%) patients in group I and in 15 of 20 patients (75%) in group II. The late loss was lower in group II than in group I (0.49±0.35 mm vs. 0.14±0.24 mm respectively, p<0.01). MACE during the 6-month follow-up developed in 8 patients (14.3%) of group I and in 1 patient (5.0%) of group II (p=0.04). Conclusion: DES is associated with a better clinical outcome than CBA for the treatment of the focal type of ISR.

KW - Coronary disease

KW - Stenosis

KW - Stents

UR - http://www.scopus.com/inward/record.url?scp=33646487515&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646487515&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33646487515

VL - 36

SP - 279

EP - 284

JO - Korean Circulation Journal

JF - Korean Circulation Journal

SN - 1738-5520

IS - 4

ER -