Competing patterns of signaling activity in Dictyostelium Discoideum

Kyoung Jin Lee, Edward C. Cox, Raymond E. Goldstein

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172 Citations (Scopus)

Abstract

Quantitative experiments are described on spatiotemporal patterns of coherent chemical signaling activity in populations of Dictyostelium discoideum amoebae. We observe competition between spontaneously tiring centers and rotating spiral waves that depends strongly on the overall cell density. At low densities, no complete spirals appear and chemotactic aggregation is driven by periodic concentric waves, whereas at high densities the firing centers seen at early times nucleate and are apparently entrained by spiral waves whose cores ultimately serve as aggregation centers. Possible mechanisms for these observations are discussed.

Original languageEnglish
Pages (from-to)1174-1177
Number of pages4
JournalPhysical Review Letters
Volume76
Issue number7
Publication statusPublished - 1996 Dec 1
Externally publishedYes

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Competing patterns of signaling activity in Dictyostelium Discoideum. / Lee, Kyoung Jin; Cox, Edward C.; Goldstein, Raymond E.

In: Physical Review Letters, Vol. 76, No. 7, 01.12.1996, p. 1174-1177.

Research output: Contribution to journalArticle

Lee, KJ, Cox, EC & Goldstein, RE 1996, 'Competing patterns of signaling activity in Dictyostelium Discoideum', Physical Review Letters, vol. 76, no. 7, pp. 1174-1177.
Lee, Kyoung Jin ; Cox, Edward C. ; Goldstein, Raymond E. / Competing patterns of signaling activity in Dictyostelium Discoideum. In: Physical Review Letters. 1996 ; Vol. 76, No. 7. pp. 1174-1177.
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