Congenital miliary tuberculosis in an 18-day-old boy

Jue Seong Lee, Chang Hoon Lim, Eunji Kim, Hyunwook Lim, Yoon Lee, Ji-Tae Choung, Young Yoo

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Congenital tuberculosis (TB) is a rare disease that is associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from the infected mother to the fetus by the transplacental route or by aspiration of infected amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns are the most common findings in the chest X-rays of many infants with congenital TB. In this case, an 18-day-old boy had jaundice on the fifth day of birth, and fever and respiratory distress appeared on the 18th day. Chest X-ray showed diffuse fine bilateral infiltration. Clinically, pneumonia or sepsis was suspected. Respiratory symptoms and chest X-ray findings worsened despite empirical antibiotic therapy. The lungs showed miliary infiltration suggestive of TB. Gastric aspirates were positive for M. tuberculosis. Respiratory distress and fever were gradually improved after anti-TB medication. Congenital TB is difficult to detect because of minimal or no symptoms during pregnancy and nonspecific symptoms in neonates. Hence, clinicians should suspect the possibility of TB infection even if neonates have non-specific symptoms. Early diagnosis and meticulous treatment are required for the survival of neonates with TB.

Original languageEnglish
Pages (from-to)S64-S67
JournalKorean Journal of Pediatrics
Volume59
DOIs
Publication statusPublished - 2016 Nov 1

Fingerprint

Miliary Tuberculosis
Tuberculosis
Thorax
X-Rays
Newborn Infant
Mycobacterium tuberculosis
Fever
Amniotic Fluid
Rare Diseases
Jaundice
Signs and Symptoms
Early Diagnosis
Sepsis
Pneumonia
Stomach
Fetus
Mothers
Parturition
Anti-Bacterial Agents
Pregnancy

Keywords

  • Congenital tuberculosis
  • Miliary pattern
  • Neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pediatrics

Cite this

Congenital miliary tuberculosis in an 18-day-old boy. / Lee, Jue Seong; Lim, Chang Hoon; Kim, Eunji; Lim, Hyunwook; Lee, Yoon; Choung, Ji-Tae; Yoo, Young.

In: Korean Journal of Pediatrics, Vol. 59, 01.11.2016, p. S64-S67.

Research output: Contribution to journalArticle

Lee, Jue Seong ; Lim, Chang Hoon ; Kim, Eunji ; Lim, Hyunwook ; Lee, Yoon ; Choung, Ji-Tae ; Yoo, Young. / Congenital miliary tuberculosis in an 18-day-old boy. In: Korean Journal of Pediatrics. 2016 ; Vol. 59. pp. S64-S67.
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