Consistent 4D cortical thickness measurement for longitudinal neuroimaging study

Yang Li, Yaping Wang, Zhong Xue, Feng Shi, Weili Lin, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Accurate and reliable method for measuring the thickness of human cerebral cortex provides powerful tool for diagnosing and studying of a variety of neuro-degenerative and psychiatric disorders. In these studies, capturing the subtle longitudinal changes of cortical thickness during pathological or physiological development is of great importance. For this purpose, in this paper, we propose a 4D cortical thickness measuring method. Different from the existing temporal-independent methods, our method fully utilizes the 4D information given by temporal serial images. Therefore, it is much more resistant to noises from the imaging and pre-processing steps. The experiments on longitudinal image datasets from the Alzheimer's Disease Neuroimaging Initiative (ADNI) show that our method significantly improves the longitudinal stability, i.e. temporal consistency, in cortical thickness measurement, which is crucial for longitudinal study. Power analysis of the correlation between cortical thickness and Mini-Mental-Status-Examination (MMSE) score demonstrated that our method generates statistically more significant results when comparing with the 3D temporal-independent thickness measuring methods.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages133-142
Number of pages10
Volume6362 LNCS
EditionPART 2
DOIs
Publication statusPublished - 2010 Nov 22
Externally publishedYes
Event13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, China
Duration: 2010 Sep 202010 Sep 24

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume6362 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
CountryChina
CityBeijing
Period10/9/2010/9/24

Fingerprint

Neuroimaging
Thickness measurement
Imaging techniques
Processing
Experiments
Power Analysis
Alzheimer's Disease
Longitudinal Study
Cortex
Psychiatry
Preprocessing
Disorder
Imaging

ASJC Scopus subject areas

  • Computer Science(all)
  • Theoretical Computer Science

Cite this

Li, Y., Wang, Y., Xue, Z., Shi, F., Lin, W., & Shen, D. (2010). Consistent 4D cortical thickness measurement for longitudinal neuroimaging study. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (PART 2 ed., Vol. 6362 LNCS, pp. 133-142). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6362 LNCS, No. PART 2). https://doi.org/10.1007/978-3-642-15745-5_17

Consistent 4D cortical thickness measurement for longitudinal neuroimaging study. / Li, Yang; Wang, Yaping; Xue, Zhong; Shi, Feng; Lin, Weili; Shen, Dinggang.

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 6362 LNCS PART 2. ed. 2010. p. 133-142 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6362 LNCS, No. PART 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Li, Y, Wang, Y, Xue, Z, Shi, F, Lin, W & Shen, D 2010, Consistent 4D cortical thickness measurement for longitudinal neuroimaging study. in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PART 2 edn, vol. 6362 LNCS, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 2, vol. 6362 LNCS, pp. 133-142, 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, Beijing, China, 10/9/20. https://doi.org/10.1007/978-3-642-15745-5_17
Li Y, Wang Y, Xue Z, Shi F, Lin W, Shen D. Consistent 4D cortical thickness measurement for longitudinal neuroimaging study. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PART 2 ed. Vol. 6362 LNCS. 2010. p. 133-142. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2). https://doi.org/10.1007/978-3-642-15745-5_17
Li, Yang ; Wang, Yaping ; Xue, Zhong ; Shi, Feng ; Lin, Weili ; Shen, Dinggang. / Consistent 4D cortical thickness measurement for longitudinal neuroimaging study. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 6362 LNCS PART 2. ed. 2010. pp. 133-142 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2).
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