Control of interparticle spacing using structured microfluidic channels

Dianne Pulido, Aram Chung, Hamed Amini, Mahdokht Masaeli, Dino Di Carlo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report a technique for controlling interparticle spacing and position for inertially-focused particles at high concentrations using structured microfluidic channels. Particle control in flow holds many applications in the development of more efficient microfluidic platforms such as in particle encapsulation for droplet microfluidics, particle separation techniques, and high-throughput flow cytometry. We have evaluated how channel structures, or localized changes to channel width, affect particle behavior and report the following modes of control: expansion and contraction of interparticle spacing, improved accuracy of focusing, and shift of equilibrium positions towards the channel walls.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages326-328
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012
Externally publishedYes
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

Keywords

  • Inertial microfluidics
  • Particle control
  • Structured channels

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Pulido, D., Chung, A., Amini, H., Masaeli, M., & Di Carlo, D. (2012). Control of interparticle spacing using structured microfluidic channels. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 326-328). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.