Core/Shell Nanoparticles for Drug Delivery and Diagnosis

Hwanbum Lee, Jae Yeon Kim, Eun Hee Lee, Young In Park, Keun Sang Oh, Kwang Meyung Kim, Ick Chan Kwon, Soon Hong Yuk

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Core/shell nanoparticles (NPs) are formed using various strategies and offer considerable advantages for diagnosis and therapy. Because of the hydrophilic nature of their shell with relatively small size, core/shell NPs have been utilized to solubilize hydrophobic drugs as well as imaging agents, improving pharmacokinetics. This chapter will introduce various types of core/shell NPs based on their preparation method and formation mechanism. The focus will be on the core/shell nanomedicine for tumor targeting, stimulated release of proteins, and cancer imaging capabilities.

Original languageEnglish
Title of host publicationNanomaterials in Drug Delivery, Imaging, and Tissue Engineering
PublisherJohn Wiley and Sons
Pages321-343
Number of pages23
ISBN (Print)9781118290323
DOIs
Publication statusPublished - 2013 Feb 18
Externally publishedYes

Keywords

  • Core/shell nanoparticles
  • Drug delivery system
  • Molecular imaging
  • Polymeric micelle
  • Temperature induced phase transition

ASJC Scopus subject areas

  • Medicine(all)
  • Engineering(all)

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  • Cite this

    Lee, H., Kim, J. Y., Lee, E. H., Park, Y. I., Oh, K. S., Kim, K. M., Kwon, I. C., & Yuk, S. H. (2013). Core/Shell Nanoparticles for Drug Delivery and Diagnosis. In Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering (pp. 321-343). John Wiley and Sons. https://doi.org/10.1002/9781118644591.ch9