Abstract
AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.
| Original language | English |
|---|---|
| Pages (from-to) | 3335-3341 |
| Number of pages | 7 |
| Journal | World Journal of Gastroenterology |
| Volume | 17 |
| Issue number | 28 |
| DOIs | |
| Publication status | Published - 2011 Jul 28 |
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Keywords
- Abdominal fat
- Computed tomography
- Steatosis
- Subcutaneous fat
- Visceral fat
ASJC Scopus subject areas
- Gastroenterology
Cite this
Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol. / Jang, Seonah; Lee, Chang-Hee; Choi, Kyung Mook; Lee, Jongmee; Choi, Jae Woong; Kim, Kyeong Ah; Park, Cheol Min.
In: World Journal of Gastroenterology, Vol. 17, No. 28, 28.07.2011, p. 3335-3341.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol
AU - Jang, Seonah
AU - Lee, Chang-Hee
AU - Choi, Kyung Mook
AU - Lee, Jongmee
AU - Choi, Jae Woong
AU - Kim, Kyeong Ah
AU - Park, Cheol Min
PY - 2011/7/28
Y1 - 2011/7/28
N2 - AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.
AB - AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.
KW - Abdominal fat
KW - Computed tomography
KW - Steatosis
KW - Subcutaneous fat
KW - Visceral fat
UR - http://www.scopus.com/inward/record.url?scp=80052020016&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052020016&partnerID=8YFLogxK
U2 - 10.3748/wjg.v17.i28.3335
DO - 10.3748/wjg.v17.i28.3335
M3 - Article
C2 - 21876622
AN - SCOPUS:80052020016
VL - 17
SP - 3335
EP - 3341
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 28
ER -