Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol

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Abstract

AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.

Original languageEnglish
Pages (from-to)3335-3341
Number of pages7
JournalWorld Journal of Gastroenterology
Volume17
Issue number28
DOIs
Publication statusPublished - 2011 Jul 28

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Abdominal Fat
Fatty Liver
Fats
Tomography
Intra-Abdominal Fat
Subcutaneous Fat
Liver
Spleen
Umbilicus
Cone-Beam Computed Tomography
Obesity

Keywords

  • Abdominal fat
  • Computed tomography
  • Steatosis
  • Subcutaneous fat
  • Visceral fat

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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title = "Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol",
abstract = "AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.",
keywords = "Abdominal fat, Computed tomography, Steatosis, Subcutaneous fat, Visceral fat",
author = "Seonah Jang and Chang-Hee Lee and Choi, {Kyung Mook} and Jongmee Lee and Choi, {Jae Woong} and Kim, {Kyeong Ah} and Park, {Cheol Min}",
year = "2011",
month = "7",
day = "28",
doi = "10.3748/wjg.v17.i28.3335",
language = "English",
volume = "17",
pages = "3335--3341",
journal = "World Journal of Gastroenterology",
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T1 - Correlation of fatty liver and abdominal fat distribution using a simple fat computed tomography protocol

AU - Jang, Seonah

AU - Lee, Chang-Hee

AU - Choi, Kyung Mook

AU - Lee, Jongmee

AU - Choi, Jae Woong

AU - Kim, Kyeong Ah

AU - Park, Cheol Min

PY - 2011/7/28

Y1 - 2011/7/28

N2 - AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.

AB - AIM: To evaluate the relationship between hepatic fat infiltration and abdominal fat volume by using computed tomography (CT). METHODS: Three hundred and six patients who visited our obesity clinic between November 2007 and April 2008 underwent fat protocol CT scans. The age range of the patients was 19 to 79 years and the mean age was 49 years. The male to female ratio was 116:190. Liver and spleen attenuation measurements were taken with three regions of interests (ROIs) from the liver and two ROIs from the spleen. Hepatic attenuation indices (HAIs) were measured as follows: (1) hepatic parenchymal attenuation (CT LP); (2) liver to spleen attenuation ratio (LS ratio); and (3) difference between hepatic and splenic attenuation (LS dif). Abdominal fat volume was measured using a 3 mm slice CT scan starting at the level of the umbilicus and was automatically calculated by a workstation. Abdominal fat was classified into total fat (TF), visceral fat (VF), and subcutaneous fat (SF). We used a bivariate correlation method to assess the relationship between the three HAIs and TF, VF, and SF. RESULTS: There were significant negative correlations between CT LP, LS ratio, and LS dif with TF, VF, and SF, respectively. The CT LP showed a strong negative correlation with TF and VF (r = -0.415 and -0.434, respectively, P < 0.001). The correlation between CTLP and SF was less significant (r = -0.313, P < 0.001). CONCLUSION: Fatty infiltration of the liver was correlated with amount of abdominal fat and VF was more strongly associated with fatty liver than SF.

KW - Abdominal fat

KW - Computed tomography

KW - Steatosis

KW - Subcutaneous fat

KW - Visceral fat

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VL - 17

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EP - 3341

JO - World Journal of Gastroenterology

JF - World Journal of Gastroenterology

SN - 1007-9327

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