Abstract
PURPOSE. To evaluate the prognostic value of grayscale parameters in fundus autofluorescence (FAF) for visual function in resolved central serous chorioretinopathy (CSC). METHODS. Seventy-six eyes of 67 patients with CSC that had been resolved for more than 4 months were analyzed retrospectively. Both the short-wavelength (SW)-FAF and near infrared (NIR)-FAF gray value parameters, including the mean, standard deviation, and coefficient of variation (CV), were calculated at 350-μm- and 1200-μm-diameter circles centered on the fovea. The FAF gray value parameters correlated with -logMAR best corrected visual acuity (BCVA) and mean microperimetry (MP) at the 2° and 4° diameters from the foveal center. RESULTS. The mean -logMAR BCVA was 0.15 ± 0.23. The mean MP was 12.87 ± 3.79 dB at 2° and 13.54 ± 3.37 dB at 4°. The -logMAR BCVA correlated most strongly with the mean SW-FAF gray value at the 350-μmcircle centered around the fovea (SW-M350; ρ 0.353; P = 0.002), and the SD of the SW-FAF gray value at the 350-μm circle centered around the fovea (SW-SD350) correlated most strongly with the MP at 2° (ρ= -0.416, P < 0.0001) and 4° (ρ= -0.435, P < 0.0001). The NIR-FAF gray value parameters did not correlate with the macular function tests. CONCLUSIONS. In subjects with resolved CSC, FAF gray values correlated with visual function. BCVA correlated most strongly with SW-M350. MP at 2° and at 4° correlated most strongly with SW-SD350.
| Original language | English |
|---|---|
| Pages (from-to) | 179-184 |
| Number of pages | 6 |
| Journal | Investigative Ophthalmology and Visual Science |
| Volume | 53 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2012 Jan 1 |
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ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
Cite this
Correlation of fundus autofluorescence gray values with vision and microperimetry in resolved central serous chorioretinopathy. / Oh, Jae Ryung; Kim, Seong-Woo; Kwon, Soon Sun; Oh, In Kyung; Huh, Kuhl.
In: Investigative Ophthalmology and Visual Science, Vol. 53, No. 1, 01.01.2012, p. 179-184.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Correlation of fundus autofluorescence gray values with vision and microperimetry in resolved central serous chorioretinopathy
AU - Oh, Jae Ryung
AU - Kim, Seong-Woo
AU - Kwon, Soon Sun
AU - Oh, In Kyung
AU - Huh, Kuhl
PY - 2012/1/1
Y1 - 2012/1/1
N2 - PURPOSE. To evaluate the prognostic value of grayscale parameters in fundus autofluorescence (FAF) for visual function in resolved central serous chorioretinopathy (CSC). METHODS. Seventy-six eyes of 67 patients with CSC that had been resolved for more than 4 months were analyzed retrospectively. Both the short-wavelength (SW)-FAF and near infrared (NIR)-FAF gray value parameters, including the mean, standard deviation, and coefficient of variation (CV), were calculated at 350-μm- and 1200-μm-diameter circles centered on the fovea. The FAF gray value parameters correlated with -logMAR best corrected visual acuity (BCVA) and mean microperimetry (MP) at the 2° and 4° diameters from the foveal center. RESULTS. The mean -logMAR BCVA was 0.15 ± 0.23. The mean MP was 12.87 ± 3.79 dB at 2° and 13.54 ± 3.37 dB at 4°. The -logMAR BCVA correlated most strongly with the mean SW-FAF gray value at the 350-μmcircle centered around the fovea (SW-M350; ρ 0.353; P = 0.002), and the SD of the SW-FAF gray value at the 350-μm circle centered around the fovea (SW-SD350) correlated most strongly with the MP at 2° (ρ= -0.416, P < 0.0001) and 4° (ρ= -0.435, P < 0.0001). The NIR-FAF gray value parameters did not correlate with the macular function tests. CONCLUSIONS. In subjects with resolved CSC, FAF gray values correlated with visual function. BCVA correlated most strongly with SW-M350. MP at 2° and at 4° correlated most strongly with SW-SD350.
AB - PURPOSE. To evaluate the prognostic value of grayscale parameters in fundus autofluorescence (FAF) for visual function in resolved central serous chorioretinopathy (CSC). METHODS. Seventy-six eyes of 67 patients with CSC that had been resolved for more than 4 months were analyzed retrospectively. Both the short-wavelength (SW)-FAF and near infrared (NIR)-FAF gray value parameters, including the mean, standard deviation, and coefficient of variation (CV), were calculated at 350-μm- and 1200-μm-diameter circles centered on the fovea. The FAF gray value parameters correlated with -logMAR best corrected visual acuity (BCVA) and mean microperimetry (MP) at the 2° and 4° diameters from the foveal center. RESULTS. The mean -logMAR BCVA was 0.15 ± 0.23. The mean MP was 12.87 ± 3.79 dB at 2° and 13.54 ± 3.37 dB at 4°. The -logMAR BCVA correlated most strongly with the mean SW-FAF gray value at the 350-μmcircle centered around the fovea (SW-M350; ρ 0.353; P = 0.002), and the SD of the SW-FAF gray value at the 350-μm circle centered around the fovea (SW-SD350) correlated most strongly with the MP at 2° (ρ= -0.416, P < 0.0001) and 4° (ρ= -0.435, P < 0.0001). The NIR-FAF gray value parameters did not correlate with the macular function tests. CONCLUSIONS. In subjects with resolved CSC, FAF gray values correlated with visual function. BCVA correlated most strongly with SW-M350. MP at 2° and at 4° correlated most strongly with SW-SD350.
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U2 - 10.1167/iovs.11-8704
DO - 10.1167/iovs.11-8704
M3 - Article
VL - 53
SP - 179
EP - 184
JO - Investigative Ophthalmology and Visual Science
JF - Investigative Ophthalmology and Visual Science
SN - 0146-0404
IS - 1
ER -