Corticosteroid treatment of pure red cell aplasia in a patient with hepatitis a

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Abstract

Secondary pure red cell aplasia (PRCA), as an extrahepatic manifestation of hepatitis A virus infection, has been reported on rare occasions. We report herein an unusual case of hepatitis A complicated by PRCA. In addition, we reviewed nine cases reported in the English literature. Our case of nonfulminant hepatitis A complicated by PRCA and hemolytic anemia was successfully treated with initial transfusion and corticosteroid therapy for 18 weeks. The patient's hematologic abnormalities and liver function tests re-normalized completely. We review clinical features and effective therapeutic strategies for this disease entity.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalActa Haematologica
Volume128
Issue number1
DOIs
Publication statusPublished - 2012 Jun

Keywords

  • Anemia
  • Corticosteroid
  • Hemolytic anemia
  • Hepatitis A
  • Pure red cell aplasia

ASJC Scopus subject areas

  • Hematology

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