Coumarin-Cu(II) ensemble-based cyanide sensing chemodosimeter

Hyo Sung Jung, Ji Hye Han, Zee Hwan Kim, Chulhun Kang, Jong Seung Kim

Research output: Contribution to journalArticle

176 Citations (Scopus)

Abstract

An "ensemble"-based chemodosimeter 1-Cu(II) for cyanide detection is reported. 1-Cu(II) can recognize a cyanide ion over other anionic species to show a marked fluorescence enhancement under aqueous conditions. "Off-on" fluorescence change of 1-Cu(II) is proceeded by addition of cyanide, which induces decomplexation of the Cu(II) ion from nonfluorescent 1 followed by hydrolytic cleavage of the resulted Schiff base to give a strongly fluorescent coumarinaldehyde (2). The selective detection of cyanide with 1-Cu(II) for biological application was also performed in HepG2 cells.

Original languageEnglish
Pages (from-to)5056-5059
Number of pages4
JournalOrganic Letters
Volume13
Issue number19
DOIs
Publication statusPublished - 2011 Oct 7

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Cyanides
cyanides
Fluorescence
Ions
fluorescence
Schiff Bases
Hep G2 Cells
imines
cleavage
ions
coumarin
augmentation
cells

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Coumarin-Cu(II) ensemble-based cyanide sensing chemodosimeter. / Jung, Hyo Sung; Han, Ji Hye; Kim, Zee Hwan; Kang, Chulhun; Kim, Jong Seung.

In: Organic Letters, Vol. 13, No. 19, 07.10.2011, p. 5056-5059.

Research output: Contribution to journalArticle

Jung, HS, Han, JH, Kim, ZH, Kang, C & Kim, JS 2011, 'Coumarin-Cu(II) ensemble-based cyanide sensing chemodosimeter', Organic Letters, vol. 13, no. 19, pp. 5056-5059. https://doi.org/10.1021/ol2018856
Jung, Hyo Sung ; Han, Ji Hye ; Kim, Zee Hwan ; Kang, Chulhun ; Kim, Jong Seung. / Coumarin-Cu(II) ensemble-based cyanide sensing chemodosimeter. In: Organic Letters. 2011 ; Vol. 13, No. 19. pp. 5056-5059.
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