Covered, retrievable, expandable urethral nitinol stent: Feasibility study in dogs

Gi Young Ko, Gab Cheol Kim, Tae Seok Seo, Tae Hyung Kim, Jin Oh Lim, Jong Heon Lee, Ho Young Song

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

PURPOSE: To evaluate the feasibility of using a retrievable urethral stent and to evaluate whether granulation tissue resolves after stent removal in a canine urethra. MATERIALS AND METHODS: Polyurethane-covered retrievable 0.10-mm-thick (n = 11) or 0.15-mm-thick (n = 10) nitinol wire stents were placed in the urethras of 20 dogs. In one dog, a second stent was placed in the urethra because of complete migration of the first stent into the urinary bladder. The stents were removed with retrieval hook wires 4 weeks (n = 10) and 8 weeks (n = 10) after placement. Fourteen dogs were sacrificed just after stent removal, and the other six dogs were sacrificed 2 weeks after stent removal. Information concerning procedure success, stent migration, and tissue response was obtained. RESULTS: Stent placement was technically successful in all dogs. Follow-up urethrograms showed partial (n = 4) or complete (n = 1) stent migration. Stent removal failed in two dogs due to partial or complete migration. Granulation tissue was observed at both ends of the stent in 17 dogs. Urethrograms and urethral specimens obtained 2 weeks after stent removal showed diminished granulation tissue and decreased thickness of the papillary projections of the epithelium compared with results obtained immediately after stent removal. CONCLUSION: Although some design modifications are necessary to reduce current complications, the polyurethane-covered retrievable nitinol stent seems feasible for use in the urethra. Stent-induced granulation tissue formation improved after stent removal.

Original languageEnglish
Pages (from-to)83-90
Number of pages8
JournalRadiology
Volume223
Issue number1
DOIs
Publication statusPublished - 2002 Jan 1

Keywords

  • Animals
  • Interventional procedures, experimental studies
  • Stents and prostheses
  • Urethra, interventional procedures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Covered, retrievable, expandable urethral nitinol stent: Feasibility study in dogs'. Together they form a unique fingerprint.

  • Cite this

    Ko, G. Y., Kim, G. C., Seo, T. S., Kim, T. H., Lim, J. O., Lee, J. H., & Song, H. Y. (2002). Covered, retrievable, expandable urethral nitinol stent: Feasibility study in dogs. Radiology, 223(1), 83-90. https://doi.org/10.1148/radiol.2231010734